Effect of prolonged ethanol intake on body weight, liver weight and liver nitrogen, glycogen, ADH, NAD and NADH of mice

Mirone, Leonora

doi:10.1016/0024-3205(65)90332-2

Cited by 14 publications

(3 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Prolonged ingestion of ethanol results in a marked accumulation of hepatic triglyceride, which was, in these experiments, associated with a marked depletion in glycogen (Table 3). These findings are in agreement with previous findings (Clarke & Evans, 1960;Mirone, 1965). Although the carbohydrate content of the diet of group 4 was greater than that of the diet given to group 3 (Table 1), chronic ingestion of ethanol still resulted in the depletion of hepatic glycogen (Table 3).…”

Section: Free Pisupporting

confidence: 93%

Biochemical aspects associated with an ethanol-induced fatty liver

Walker

Gordon

1970

Biochemical Journal

View full text Add to dashboard Cite

Isocaloric replacement of either the fat or carbohydrate content of the diet by ethanol (36% of the total caloric intake) produced fatty infiltration of the liver in rats. The increase in hepatic triglyceride content was associated with a decrease in both ATP and glycogen contents. Increased activity of mitochondrial Mg(2+)-stimulated adenosine triphosphatase paralleled the increase in the free P(i) content of the liver homogenate. During the regression of the fatty liver, glycogen contents returned to normal within 24h of the removal of ethanol from the diet. Not until the third day after the withdrawal of ethanol had the Mg(2+)-stimulated adenosine triphosphatase activity and free P(i) content of the homogenate returned to normal. A slow regression of the triglyceride content from the liver occurred and by the fifth day both ATP and triglyceride concentrations had returned to the values observed in the rats given the liquid control diet.

show abstract

Section: Free Pisupporting

confidence: 93%

Biochemical aspects associated with an ethanol-induced fatty liver

Walker

Gordon

1970

Biochemical Journal

View full text Add to dashboard Cite

show abstract

“…Inhibition of glycogen synthesis at the glycogen synthetase level during Q fever raises the question of the status of other key intermediate metabolites in glycogen synthesis. The wide occurrence of overtly similar pathologies in bacterial and protozoan infections (16,24) and during pharmacological damage (17) suggests operation of some common factor or factors during liver damage. Stress could be a factor because of its influence on hormonal levels and hormonal roles in metabolic regulation (23,27).…”

mentioning

confidence: 99%

Changes in Hepatic Glycogen, Protein, and Ribonucleic Acid Synthesis, and Some Effects of Cortisol, During Q Fever

Stueckemann

Paretsky

1971

J Bacteriol

View full text Add to dashboard Cite

Liver glycogen is depleted in guinea pigs infected with Coxiella burneti. Syntheses of the glycogen precursors uridine triphosphate and uridine diphosphate glucose are unaffected during Q fever, but glycogen synthetase activity is inhibited. Exogenous cortisol relieves this inhibition in infected animals. Orotate and amino acids are more rapidly incorporated into ribonucleic acid and protein during infection. It is proposed that the biochemical defect in the synthesis of glycogen lies in the inactivation of glycogen synthetase.

show abstract

“…Thus, addition of this compound to the diet may result in energy accumulation and consequently weight gain. However, a search in the literature using ethanol versus body weight lead us to several scientific studies from the 60's to the 90's reporting that ethanol does not interfere in weight gain [26][27][28][29].…”

Section: Ethanol and Its Effectsmentioning

confidence: 99%

Influence of Clove Tea (Syzygium Aromaticum) on Body Weight and Biochemical Parameters of Rats Subjected to Ethanol Consumption and Abstinence

Mani¹,

Braga²,

Novelli³

et al. 2012

Med Chem

View full text Add to dashboard Cite

Clove has a large number of therapeutic properties and its tea has been used by the general population as antiinflammatory, antihyperglycemic, antimutagenic, bactericidal, and nematicidal, among others. Thus, the aim of this study was to assess the effect of clove on biochemical parameters of rats subjected to ethanol consumption and abstinence. The animals were subjected to ethanol intake before and after treatment with clove tea, according to their groups, as follows: GW received water (control); GE received 3% ethanol alone; GC received clove alone; GCE received clove for 7 consecutive days followed by 3% ethanol for 16 consecutive days; GEC received 3% ethanol for 16 consecutive days followed by clove for 7 consecutive days. Administration of clove tea alone or ethanol alone did not change serum parameters such as glucose, triglycerides, total cholesterol, total protein and albumin, and it did not alter weight gain although there was a significant difference in mean food consumption, which suggests that under such conditions clove tea or ethanol does not interfere with these parameters. On the other hand, administration of clove tea before or after ethanol administration led to significant changes in several parameters such as glucose, triglycerides, cholesterol, total protein and albumin. The obtained results thus suggest that prolonged ethanol intake should be avoided when clove tea is consumed daily.

show abstract

Effect of prolonged ethanol intake on body weight, liver weight and liver nitrogen, glycogen, ADH, NAD and NADH of mice

Cited by 14 publications

References 10 publications

Biochemical aspects associated with an ethanol-induced fatty liver

Biochemical aspects associated with an ethanol-induced fatty liver

Changes in Hepatic Glycogen, Protein, and Ribonucleic Acid Synthesis, and Some Effects of Cortisol, During Q Fever

Influence of Clove Tea (Syzygium Aromaticum) on Body Weight and Biochemical Parameters of Rats Subjected to Ethanol Consumption and Abstinence

Contact Info

Product

Resources

About