Effect of propolis on human cartilage and chondrocytes

Cardile, Venera; Panico, Annamaria; Gentile, Barbara Cristina; Borrelli, Francesca; Russo, Alessandra

doi:10.1016/s0024-3205(03)00381-3

Cited by 49 publications

(34 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It has been shown that PGE 2 was able to inhibit chondrocyte growth, and upregulate IL-1h (Manfield et al, 2000). In the last years we looked for novel anti-inflammatory/chondroprotective agents from natural products (Cardile et al, 2003) able to act on multiple targets in inflammatory diseases. Assays were conducted with cultured human chondrocytes to screen for new potentially active natural substances.…”

Section: Discussionmentioning

confidence: 99%

Protective effect of Capparis spinosa on chondrocytes

et al. 2005

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Protective effect of Capparis spinosa on chondrocytes

et al. 2005

View full text Add to dashboard Cite

“…The activation of NF-κB by TNF can be dose-and timedependently blocked by CAPE (59). CAPE can also be used as a lipoxygenase inhibitor, performing anti-oxidation (60,61) and anti-inflammatory activity (62). Recently, we have shown that CAPE-like compounds exhibited different effects on anti-HIV replication and cytokine modulation (63).…”

Section: Anti-microbe and Anti-cancer Effectsmentioning

confidence: 99%

The Immunopharmaceutical Effects and Mechanisms of Herb Medicine

Huang¹,

Lin

Liao

et al. 2008

Cell Mol Immunol

View full text Add to dashboard Cite

In recent years, studies on evaluation of the therapeutic and toxic activity of herbal medicinal products became available and popular. The advances in modern biotechnology have led to discovery of many new active constituents. However, it is a constant challenge to establish the pharmacological basis for efficacy and safety of herbal medicinal products. A better understanding of the effects and bioavailability of phytopharmaceuticals can help in discovering suitable and rational therapies. In this review, we present the bioavailability studies in immune system that has been conducted for some of the more important or widely used phytopharmaceuticals. Furthermore, various new drug targets worthy of using for drug development in immunomodulating herbal medicine area and their regulatory mechanisms are also discussed. Adverse effects, drug interactions, and contraindications are also discussed which show that caution should be exercised when combining phytopharmaceuticals with chemically derived pharmaceutical components. Cellular & Molecular Immunology. 2008;5(1):23-31.

show abstract

“…Use of products containing propolis by humans has a long history because of its beneficial effects in many pathological processes (Burdock, 1998). In fact, numerous papers have reported a broad spectrum of biological activities such as antibiotic, antifungal, antiviral (Kujumgiev et al, 1999), antiinflammatory (Park and Kahng, 1999;Ozturk et al, 2000;Borrelli et al, 2002;Cardile et al, 2003), immunomodulatory (Bratter et al, 1999), antitumor and antioxidant effects (Scheller et al, 1990;Russo et al, 2002). The antimutagenic effect of ethanolic extract of propolis has also been demonstrated in the Salmonella microsome treated with benzo[a]pyrene, a polycyclic aromatic hydrocarbon found at high concentrations in cigarette smoke (Varanda et al, 1999).…”

Section: Introductionmentioning

confidence: 99%