Effect of Prostacyclin Infusion in Severe Pre-Eclampsia

Toppozada, M.; Khowessah, M.; Shaala, S.; Shalaby, Thanaa I.

doi:10.3109/10641958609031666

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1988

1991

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Cited by 6 publications

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“…1). The therapeutic investigations for the effect of exogenous prostacyclin have demonstrated mixed re sults; although maternal blood pressure was effectively lowered by prostacyclin infusion, there were a number of stillbirths [5]. Our animal experiments which we con ducted to investigate the effects of prostacyclin-induced OP-41483 on the rat's placental blood flow by measuring the clearance of hydrogen gas generated by electrolysis produced the following results: in normal pregnant rats systolic blood pressure did not change significantly, in pregnant spontaneously hypertensive rats systolic blood pressure decreased and placental blood flow also de creased significantly [6].…”

Section: Discussionmentioning

confidence: 99%