1968
DOI: 10.1016/0002-9378(68)90002-1
|View full text |Cite
|
Sign up to set email alerts
|

Effect of prostaglandin E1 on the midpregnant human uterus

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1

Citation Types

0
10
1

Year Published

1970
1970
1986
1986

Publication Types

Select...
4
3

Relationship

1
6

Authors

Journals

citations
Cited by 54 publications
(11 citation statements)
references
References 7 publications
0
10
1
Order By: Relevance
“…Hence it is fairly well possible that the threshold dose of this substance might #be lower than 50 pg. The threshold dose for PGE, is approximately the same in midpregnant and non-pregnant women (22). The technical prerequisites for quantitative evaluation are not identical in these experiments.…”
Section: Discussionmentioning
confidence: 98%
See 1 more Smart Citation
“…Hence it is fairly well possible that the threshold dose of this substance might #be lower than 50 pg. The threshold dose for PGE, is approximately the same in midpregnant and non-pregnant women (22). The technical prerequisites for quantitative evaluation are not identical in these experiments.…”
Section: Discussionmentioning
confidence: 98%
“…The isolated pure prostaglandin compounds may be administered intravenously by single injections. Such injections given to pregnant patients under in vivo conditions result in an immediate stimulatory response which is reproducible, dose related and easy to evaluate quantitatively (3,22).…”
mentioning
confidence: 96%
“…Twenty-milligrams PGE, or 50-mg. PGFz, vaginal tablets were prepared by the addition of alcoholic solutions of the drug onto lactose tablets. Lower doses of PGEl (0.20-1 .O mg.) were not effective in stimulating the uterus in six women between the 14th and 20th week of pregnancy (243). until abortion took place.…”
Section: Biologymentioning
confidence: 88%
“…Using pregnant human myometrium, Embrey and Morrison (241) reported that both PGEz and PGFz, stimulated myometrial contractility in vitro. In vivo administration of PGEI, PGE2, PGFl,, and PGF2, had a stimulatory effect on the uterus (242)(243)(244)(245). In vivo administration of PGEI, PGE2, PGFl,, and PGF2, had a stimulatory effect on the uterus (242)(243)(244)(245).…”
Section: Biologymentioning
confidence: 97%
“…Instillation of semen or seminal fluid extract into the vagina of pregnant women during the second trimester of pregnancy has no stimulant effect on the uterus (Wiqvist et al, 1968;. Since the discovery of prostaglandins in the semen it has been assumed that these substances through their uterine stimulant action could induce premature labour.…”
Section: Intercourse and Premature Labourmentioning
confidence: 99%