1968
DOI: 10.1093/jn/95.2.173
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Effect of Protein Deficiency on the Spleen and Antibody Formation in Rats

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1969
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Cited by 79 publications
(28 citation statements)
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“…The interaction between malnutrition and immunity has been studied extensively both in experimental animals [5][6][7][8] and in humans [9][10][11]. Variable results have been found, some studies showed impaired anti body production [6,8,9,11] and others nor mal levels of antibody production [5,7,11].…”
Section: Introductionmentioning
confidence: 99%
“…The interaction between malnutrition and immunity has been studied extensively both in experimental animals [5][6][7][8] and in humans [9][10][11]. Variable results have been found, some studies showed impaired anti body production [6,8,9,11] and others nor mal levels of antibody production [5,7,11].…”
Section: Introductionmentioning
confidence: 99%
“…Interest in the effect of diet on immunity, malignancy and longevity has been expressed through the years (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15). McCay et al (16) showed that placing weanling rats on a diet restricted in calories promotes longevity.…”
mentioning
confidence: 99%
“…It was also possible that the maturation of B-cells to plasma cells and/or the antibody-producing capacity of individual plasma cells were affected. However, Kenney et al (1968) reported that alterations in antibody responses in undernourished rats were not due to altered antibody production by individual cells. The fact that total serum immunoglobulin concentrations were unchanged by the weaning/nutrition treatments suggested that the effects on antibody responses were not due to changes in the catabolism of immunoglobulins.…”
Section: Discussionmentioning
confidence: 99%