Effect of Pulsed Nd:YAG Laser in the Treatment of Neuropathic Foot Ulcers in Children with Spina Bifida: A Randomized Controlled Study

Abstract

Treatment with pulsed neodymium:yttrium aluminum garnet (Nd:YAG) laser combined with standard wound care decreases wound size and improves wound appearance for stage III neuropathic foot ulcers in children with spina bifida.

Efficacy of high intensity laser therapy in the management of foot ulcers: a systematic review

“…Following the removal of duplicate articles, 251 articles were screened by reading the titles and abstracts. Seven articles were initially eligible and after full text assessment, only three studies 19 , 20 , 21 ) met the inclusion criteria, while four articles were excluded because they used low level laser therapy (LLLT). Figure 1

Fig.

…”

“…Three studies 19 , 20 , 21 ) with a total of 122 patients were included in this review, all of which were published during the last ten years. Two studies investigated the effect of HILT in patients with diabetic foot ulcers 19 , 20 ) and the third study was conducted on spina bifida children with neuropathic foot ulcers 21 ) . All studies assessed the efficacy of the intervention on WSA, while wound appearance (WA) was assessed in only one study 21 ) .…”

“…Two studies investigated the effect of HILT in patients with diabetic foot ulcers 19 , 20 ) and the third study was conducted on spina bifida children with neuropathic foot ulcers 21 ) . All studies assessed the efficacy of the intervention on WSA, while wound appearance (WA) was assessed in only one study 21 ) . All studies used HILT as the main intervention compared with sham laser in two studies 20 , 21 ) , while one study assessed HILT versus standard medical therapy 19 ) .…”

Some Morphological and Functional Aspects of Chronic Osteomyelitis in Patients with Neurogenic Foot Deformities

“…Полученные нами результаты исследования раскрывают особенности строения и свойств кожи при спинальной дизрафии (spina bifida) и объясняют механизмы формирования глубоких язв стопы и развития остеомиелита у данной категории больных. Известно, что у больных со spina bifida (тип myelomeningocele) существует повышенный риск развития нейропатических язв стопы [11][12][13][14]19]. Результаты исследования показали, что первостепенное значение имеет неврологический дефицит.…”

“…Первичный неврологический дефицит приводит не только к нарушениям походки и функции, но и к вторичной патологии опорно-двигательного аппарата, в том числе контрактурам, костным деформациям, нестабильности и дегенерации сус тавов [10]. Такой спектр функциональных и нев рологических расстройств является фактором повышенного риска развития нейропатических язв стопы, встречающихся у 61% пациентов со spina bifida [11][12][13][14].…”