Effect of purified zearalenone with or without modified montmorillonite on nutrient availability, genital organs and serum hormones in post-weaning piglets

Jiang, Shuzhen; Yang, Zaibin; Yang, Weiren; Wang, S.J.; Liu, F.X.; Johnston, L. A.; Feng, Cheng; Wang, Y.

doi:10.1016/j.livsci.2011.11.004

Cited by 46 publications

(46 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…James and Smith (1982) reported that ZON up to 40 mg kg −1 did not affect feed consumption of pigs and this result was in agreement with other reports that suggested no adverse effect of ZON on feed intake when gilts or weaning pigs were fed 1 to 2 mg kg −1 of ZON (Rainey et al, 1990;Jiang et al, 2012). In addition, dietary ZON may negatively affect feed intake when combined with dietary DON, but not ZON solely (Young et al, 1981;Williams and Blaney, 1994).…”

Section: Discussionsupporting

confidence: 86%

EFFECTS OF NATURALLY PRODUCED DIETARY <i>FUSARIUM</i> MYCOTOXINS ON WEANING PIGS

Shin

Kong

Kim³

et al. 2014

American Journal of Animal and Veterinary Sciences

View full text Add to dashboard Cite

Mycotoxins reduce animal productivity and animal health. The influence of Fusarium mycotoxins in corn co-products on pig performance is an important issue in swine feed industry. This study was conducted to determine the effects of naturally produced Fusarium mycotoxins in Corn Gluten Meal (CGM) on growth performance of nursery pigs. A total 96 weaning pigs comprising 48 gilts and 48 barrows with an initial body weight of 5.08 kg (SD = 1.28) were grouped into 3 blocks in each sex by initial body weight and randomly allotted to 4 treatments in a randomized complete block design. There were 6 replicate pens per treatment and 4 pigs were housed in each pen. The 4 experimental diets mainly based on corn, CGM, dried whey and soybean meal were formulated to contain 4 concentrations of mycotoxins derived from the contaminated CGM. Diet 1 contained 32 µg kg −1 Deoxynivalenol (DON) and 6 µg kg During the overall experimental period, both ADG and ADFI linearly depressed with increasing concentration of mycotoxins (p<0.05).In conclusion, the current study showed that dietary Fusarium mycotoxins derived from contaminated CGM by Fusarium fungi resulted in decreased growth performance of nursery pigs. Swine nutritionists may increase nutrient concentrations of diets to partially overcome the negeative effects of Fusarium mycotoxins in corn co-products on feed intake of pigs.

show abstract

Section: Discussionsupporting

confidence: 86%

EFFECTS OF NATURALLY PRODUCED DIETARY <i>FUSARIUM</i> MYCOTOXINS ON WEANING PIGS

Shin

Kong

Kim³

et al. 2014

American Journal of Animal and Veterinary Sciences

View full text Add to dashboard Cite

show abstract

“…There are many investigations that reported the effects of Fusarium mycotoxins on growth rates and metabolism in gilts [31,39,40]. However, research is limited about the effects of Fusarium mycotoxins (ZEN) on reproductive performance of pregnant sows.…”

Section: Discussionmentioning

confidence: 99%

“…The treatment groups included the following: (1) control; (2) contaminated grains (instead of 50% corn contaminated with mold); and (3) contaminated grains (instead of 50% corn contaminated with mold) þ 1% MHNTs. The doses of MHNTs were selected based on the work of Jiang et al [39,40]. The feedstuffs were subjected to postprocessing analytical control.…”

Section: Animals Exposure To Zen and The Experimental Designmentioning

confidence: 99%

Use of modified halloysite nanotubes in the feed reduces the toxic effects of zearalenone on sow reproduction and piglet development

et al. 2015

View full text Add to dashboard Cite

“…The protective effects of MHNTs may be explained by the ability of this absorbent to bind ZEN in the gastrointestinal tract and thereby reduce the toxin's bioavailability. Jiang et al (2012) mentioned that ZEN induces deleterious effects on nutrient availability, genital organs and serum hormones in piglets and that these effects are ameliorated by the dietary supplementation of modified montmorillonite. Therefore, MHNTs may be the better absorbent for the reduction of the toxic effects of ZEN and the alleviation of the contamination of feed mixtures.…”

Section: Discussionmentioning

confidence: 99%

“…The pregnant sows were divided into three treatment groups, which had mean initial body weights of 185.93 ± 3.57, 191.20 ± 2.61 and 187.37 ± 2.49 kg. The three treatments were the following (Table 1): (1) basal diet (control group), (2) ZEN-contaminated grains (instead of 50% mouldy corn), and (3) contaminated grains (instead of 50% mouldy corn) + 1% MHNTs (Jiang et al 2010(Jiang et al , 2012. The pregnant sows (six per treatment) were fed different treatment diets from days 35 to 70 of gestation and a basal diet on the remaining days of gestation.…”

Section: Experimental Design and Dietsmentioning

confidence: 99%

Alleviation of zearalenone toxicity by modified halloysite nanotubes in the immune response of swine

Yin

Meng

Zhang

et al. 2014

Food Additives & Contaminants: Part A

View full text Add to dashboard Cite

Zearalenone (ZEN) has caused significant economic effects on swine production in China. There is growing concern that exposure to ZEN during pregnancy affects the health of the offspring due to changes in the development of the immune system. To assess the risks associated with maternal ZEN exposure, several immunological parameters were assessed in pregnant sows and their offspring. The main aim of the study was to determine if modified hallosite nanotubes (MHNTs) can be used to protect pigs against the adverse effects of ZEN. Eighteen pregnant sows (second parity Yorkshire sows) were randomly divided into three treatment groups: (1) basal diet (control group); (2) contaminated grain (instead of 50% mouldy corn); and (3) contaminated grain (instead of 50% mouldy corn) + 1% MHNTs. The pregnant sows were fed the different treated diets from days 35 to 70 of gestation. Dietary ZEN exposure decreased the organ coefficient and the mRNA expression levels of IFN-γ, TNF-α, and IL-10, and increased ZEN residues and IL-4 mRNA expression in the spleen of pregnant sows and neonatal piglets. Decreases in the serum IgA and IgG levels were observed in the pregnant sows. Maternal ZEN exposure decreased the organ coefficient and the mRNA expression levels of IFN-γ and IL-10, and increased IL-4 mRNA expression in the spleen of weaning piglets. Exposure to ZEN during pregnancy decreased the level of serum IgG in the weaning piglets. Maternal exposure to ZEN induced histopathological damage and oxidative stress in the spleens of pregnant sows and their piglets. The addition of MHNTs to ZEN-contaminated diets can mitigate the negative effects induced by ZEN in the swine.

show abstract

Effect of purified zearalenone with or without modified montmorillonite on nutrient availability, genital organs and serum hormones in post-weaning piglets

Cited by 46 publications

References 38 publications

EFFECTS OF NATURALLY PRODUCED DIETARY <i>FUSARIUM</i> MYCOTOXINS ON WEANING PIGS

EFFECTS OF NATURALLY PRODUCED DIETARY <i>FUSARIUM</i> MYCOTOXINS ON WEANING PIGS

Use of modified halloysite nanotubes in the feed reduces the toxic effects of zearalenone on sow reproduction and piglet development

Alleviation of zearalenone toxicity by modified halloysite nanotubes in the immune response of swine

Contact Info

Product

Resources

About