Effect of qigong exercise and acupressure rehabilitation program on pulmonary function and respiratory symptoms in patients hospitalized with severe COVID-19: A randomized controlled trial

Liu, Shu-ting; Zhan, Cheng; Ma, Yun-jing; Guo, Chao-yang; Chen, W; Fang, Xiaoming; Fang, Lei

doi:10.1016/j.imr.2021.100796

Cited by 20 publications

(46 citation statements)

References 27 publications

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“…China is the birthplace of traditional kung fu. The study applied the qigong exercise (Liu Zi Jue) under the guidance of remote video combined with acupuncture therapy to the treatment of severe COVID-19 patients and found that patients' symptoms, such as dyspnea and cough, were significantly improved, and their hospital stay was shortened ( 11 ).…”

Section: Resultsmentioning

confidence: 99%

Knowledge Structure and Emerging Trends of Telerehabilitation in Recent 20 Years: A Bibliometric Analysis via CiteSpace

Zheng

Hou

Liu

et al. 2022

Front. Public Health

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PurposeTelerehabilitation, as an effective means of treatment, is not inferior to traditional rehabilitation, and solves the problem of many patients who do not have access to hospital-based training due to costs and distance. So far, the knowledge structure of the global use of telerehabilitation has not been formed. This study aimed to demonstrate the state of emerging trends and frontiers concerning the studies of telerehabilitation through bibliometric software.MethodsLiterature about telerehabilitation from 2000 to 2021 was retrieved from the Web of Science Core Collection. We used CiteSpace 5.8.R3 to analyze the publication years, journals/cited journals, countries, institutions, authors/cited authors, references, and keywords. Based on the analysis results, we plotted the co-citation map to more intuitively observe the research hotspots and knowledge structure.ResultsA total of 1,986 records were obtained. The number of annual publications gradually increased over the investigated period. The largest increase occurred between 2019 and 2020. J TELEMED TELECARE was the most prolific and the most cited journal. The United States was the most influential country, with the highest number of publications and centrality. The University of Queensland was the most productive institution. The author Tousignant M ranked the highest in the number of publications and Russell TG ranked the first in the cited authors. Respectively, the articles published by Cottrell MA and Russell TG ranked the first in the frequency and centrality of cited references. The four hot topics in telerehabilitation were “care”,“stroke”, “telemedicine” and “exercise”. The keyword “stroke” showed the strongest citation burst. The two frontier keywords were “physical therapy” and “participation”. The keywords were clustered to form 21 labels.ConclusionThis study uses visualization software CiteSpace to provide the current status and trends in clinical research of telerehabilitation over the past 20 years, which may help researchers identify new perspectives concerning potential collaborators and cooperative institutions, hot topics, and research frontiers in the research field. Bibliometric analysis of telerehabilitation supplements and improves the knowledge field of telemedicine from the concept of rehabilitation medicine and provides new insights into therapists during the COVID-19 pandemic.

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Section: Resultsmentioning

confidence: 99%

Knowledge Structure and Emerging Trends of Telerehabilitation in Recent 20 Years: A Bibliometric Analysis via CiteSpace

Zheng

Hou

Liu

et al. 2022

Front. Public Health

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“…However, other forms of telerehabilitation components are yet to be investigated. In addition, one study ( 41 ) reported that remote qigong exercise plus acupressure improved pulmonary function and cough in patients with severe COVID-19 and reduced hospital stay. However, we cannot separate the efficacy of remote qigong exercise from acupressure and therefore this study was excluded.…”

Section: Discussionmentioning

confidence: 99%

Do patients with and survivors of COVID-19 benefit from telerehabilitation? A meta-analysis of randomized controlled trials

Huang

Fan

Zhao

et al. 2022

Front. Public Health

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BackgroundCoronavirus disease 2019 (COVID-19) significantly impacts physical, psychological, and social functioning and reduces quality of life, which may persist for at least 6 months. Given the fact that COVID-19 is a highly infectious disease and therefore healthcare facilities may be sources of contagion, new methods avoiding face-to-face contact between healthcare workers and patients are urgently needed. Telerehabilitation is the provision of rehabilitation services to patients at a distance via information and communication technologies. However, high-quality evidence of the efficacy of telerehabilitation for COVID-19 is still lacking. This meta-analysis aimed to investigate the efficacy of telerehabilitation for patients with and survivors of COVID-19.MethodsWe searched the Cochrane Library, EMBASE, Medline (via PubMed), PEDro, ClinicalTrials.gov, and WHO International Clinical Trials Registry Platform from January 1st, 2020 to April 30th, 2022 for randomized controlled trials published in English, which aimed to evaluate the efficacy of telerehabilitation vs. face-to-face rehabilitation, usual care, or no treatment for COVID-19. Methodological quality and overall evidence quality of the included studies were assessed. The statistical reliability of the data was quantified using the trial sequential analysis.ResultsSeven randomized controlled trials with eight comparisons were included and all of them were used for meta-analysis. The meta-analyses of absolute values showed the superiority of telerehabilitation over no treatment or usual care for dyspnea (Borg scale: mean difference = −1.88, −2.37 to −1.39; Multidimensional dyspnea-12: mean difference = −3.70, −5.93 to −1.48), limb muscle strength (mean difference = 3.29; 2.12 to 4.47), ambulation capacity (standardized mean difference = 0.88; 0.62 to 1.14), and depression (mean difference = −5.68; −8.62 to −2.74). Significant improvement in these variables persisted in the meta-analyses of change scores. No significant difference was found in anxiety and quality of life. No severe adverse events were reported in any of the included studies.ConclusionsModerate- to very low-quality evidence demonstrates that telerehabilitation may be an effective and safe solution for patients with and survivors of COVID-19 in dyspnea, lower limb muscle strength, ambulation capacity, and depression. Further well-designed studies are required to evaluate the long-term effects, cost-effectiveness, and satisfaction in larger samples.

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“…Twenty-one studies enrolled 12,981 patients (446 patients in RCTs and 12,531 patients in observational studies), with a mean age of 57.21 years and a mean proportion of men of 47.91%. Thirteen studies (3 RCTs (Hu F. et al, 2021;Liu S. T. et al, 2021;Luo et al, 2021) and 10 observational studies (Qin et al, 2020;Wang et al, 2021a;Wang et al, 2021b;Feng et al, 2021;Shu et al, 2021;Sun et al, 2021;Zhang L. et al, 2021;Xiong et al, 2022)) reported on comorbidities; the most common comorbidities were diabetes, hypertension, cardiovascular disease or coronary heart disease, and respiratory conditions. All patients recruited were from China, of which 76.19% were in the Hubei Province (Chen G. et al, 2020;Wang et al, 2021a;Wang et al, 2021b;Feng et al, 2021;Hu F. et al, 2021;Huang et al, 2021;Liu, 2021;Liu S. T. et al, 2021;Luo et al, 2021;Shu et al, 2021;Sun et al, 2021;Zhang L. et al, 2021;Zhang and Pan, 2021;Zhou et al, 2021;Xiong et al, 2022), and the time was concentrated at the beginning of the pandemic outbreak (January to May 2020).…”

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

“…Thirteen studies (3 RCTs (Hu F. et al, 2021;Liu S. T. et al, 2021;Luo et al, 2021) and 10 observational studies (Qin et al, 2020;Wang et al, 2021a;Wang et al, 2021b;Feng et al, 2021;Shu et al, 2021;Sun et al, 2021;Zhang L. et al, 2021;Xiong et al, 2022)) reported on comorbidities; the most common comorbidities were diabetes, hypertension, cardiovascular disease or coronary heart disease, and respiratory conditions. All patients recruited were from China, of which 76.19% were in the Hubei Province (Chen G. et al, 2020;Wang et al, 2021a;Wang et al, 2021b;Feng et al, 2021;Hu F. et al, 2021;Huang et al, 2021;Liu, 2021;Liu S. T. et al, 2021;Luo et al, 2021;Shu et al, 2021;Sun et al, 2021;Zhang L. et al, 2021;Zhang and Pan, 2021;Zhou et al, 2021;Xiong et al, 2022), and the time was concentrated at the beginning of the pandemic outbreak (January to May 2020). Fourteen studies (4 RCTs (Hu F. et al, 2021;Liu S. T. et al, 2021;Luo et al, 2021;Zhou et al, 2021) and 10 observational studies (Zhao et al, 2020b;Chen G. et al, 2020;Wang et al, 2021a;Wang et al, 2021b;Feng et al, 2021;Huang et al, 2021;Shu et al, 2021;…”

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

“…All patients recruited were from China, of which 76.19% were in the Hubei Province (Chen G. et al, 2020;Wang et al, 2021a;Wang et al, 2021b;Feng et al, 2021;Hu F. et al, 2021;Huang et al, 2021;Liu, 2021;Liu S. T. et al, 2021;Luo et al, 2021;Shu et al, 2021;Sun et al, 2021;Zhang L. et al, 2021;Zhang and Pan, 2021;Zhou et al, 2021;Xiong et al, 2022), and the time was concentrated at the beginning of the pandemic outbreak (January to May 2020). Fourteen studies (4 RCTs (Hu F. et al, 2021;Liu S. T. et al, 2021;Luo et al, 2021;Zhou et al, 2021) and 10 observational studies (Zhao et al, 2020b;Chen G. et al, 2020;Wang et al, 2021a;Wang et al, 2021b;Feng et al, 2021;Huang et al, 2021;Shu et al, 2021;Sun et al, 2021;Zhang L. et al, 2021)) were published in English, and 8 (5 RCTs (Wen et al, 2020;Hu F. et al, 2021;Liu S. T. et al, 2021;Luo et al, 2021;Zhou et al, 2021) and 3 observational studies (Chen G. et al, 2020;Sun et al, 2021)) were registered prospectively. Additional file 1: Supplementary Table S3 presents the detailed study characteristics.…”

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

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Role of Traditional Chinese Medicine in Treating Severe or Critical COVID-19: A Systematic Review of Randomized Controlled Trials and Observational Studies

Zhu

Liu

et al. 2022

Front. Pharmacol.

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Background: The coronavirus disease 2019 (COVID-19) continues to spread globally. Due to the higher risk of mortality, the treatment of severe or critical patients is a top priority. Traditional Chinese medicine (TCM) treatment has played an extremely important role in the fight against COVID-19 in China; a timely evidence summary on TCM in managing COVID-19 is crucial to update the knowledge of healthcare for better clinical management of COVID-19. This study aimed to assess the effects and safety of TCM treatments for severe/critical COVID-19 patients by systematically collecting and synthesizing evidence from randomized controlled trials (RCTs) and observational studies (e.g., cohort).Methods: We searched nine databases up to 19th March 2022 and the reference lists of relevant publications. Pairs of reviewers independently screened studies, extracted data of interest, and assessed risk of bias. We performed qualitative systematic analysis with visual presentation of results and compared the direction and distribution of effect estimates for each patient’s important outcome. We performed sensitivity analyses to observe the robustness of results by restricting analysis to studies with low risk of bias.Results: The search yielded 217,761 records, and 21 studies (6 RCTs and 15 observational studies) proved eligible. A total of 21 studies enrolled 12,981 severe/critical COVID-19 patients with a mean age of 57.21 years and a mean proportion of men of 47.91%. Compared with usual supportive treatments, the effect estimates of TCM treatments were consistent in direction, illustrating that TCM treatments could reduce the risk of mortality, rate of conversion to critical cases, and mechanical ventilation, and showed significant advantages in shortening the length of hospital stay, time to viral clearance, and symptom resolution. The results were similar when we restricted analyses to low-risk-bias studies. No serious adverse events were reported with TCM treatments, and no significant differences were observed between groups.Conclusion: Encouraging evidence suggests that TCM presents substantial advantages in treating severe/critical COVID-19 patients. TCM has a safety profile that is comparable to that of conventional treatment alone. TCMs have played an important role in China’s prevention and treatment of COVID-19, which sets an example of using traditional medicine in preventing and treating COVID-19 worldwide.

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Effect of qigong exercise and acupressure rehabilitation program on pulmonary function and respiratory symptoms in patients hospitalized with severe COVID-19: A randomized controlled trial

Cited by 20 publications

References 27 publications

Knowledge Structure and Emerging Trends of Telerehabilitation in Recent 20 Years: A Bibliometric Analysis via CiteSpace

Knowledge Structure and Emerging Trends of Telerehabilitation in Recent 20 Years: A Bibliometric Analysis via CiteSpace

Do patients with and survivors of COVID-19 benefit from telerehabilitation? A meta-analysis of randomized controlled trials

Role of Traditional Chinese Medicine in Treating Severe or Critical COVID-19: A Systematic Review of Randomized Controlled Trials and Observational Studies

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