Effect of radiation from personal computer monitor on free-radical processes in rats

Abstract

Radiation from a personal computer monitor reduces antioxidant activity and the contents of diene conjugates and Schiff bases in rat serum and has no effect on chemiluminescence and the content of carbonyl derivatives. The radiation causes no significant changes in blood contents of nitrites and ceruloplasmin and activity of Cu,Zn-superoxide disnmtase. The results obtained indicate that radiation from a monitor produces potentially hazardous biological effects. Key Words: monitor; lipid peroxidation; antioxidant systemsThe problems associated with biological effects of radiation from a personal computer monitor (PCM) have been discussed in the literature [1,8,13]. A PC user is exposed to electromagnetic field (EMF), visible and ultraviolet light, radio-range waves, and low-frequency fields (50 Hz) and their harmonics [8]. Preliminary experiments showed that EMF of varied frequency and intensity activates some oncogenes, suppresses the immune system, causes neurologic disorders, impairs the function of hypothalamohypophyseal system, and increases the risk of tumorigenesis [7,13]. The incidence of premature births and infants born with pathologies and the risk of brain tumors are higher for PC operators [13]. The PCM radiation stimulates the growth of urethane-induced lung tumors in mice [2]. Modification of free-radical processes in the organism may be a key factor in the mechanism of biological effects of PCM radiation. These processes play an important role in age-related pathologies, atherosclerosis, ilmnunodepression, and tumorigenesis. As we are aware, the effects of PCM radiation on free-radical oxidation and antioxidant systems have not been investigated. The present study is an attempt to examine these effects. MATERIALS AND METHODSExperiments were performed on 40 male 3-monthold LIO rats bred at the N. N. Petrov Institute of Oncology. The rats were maintained in polypropylene cages (55x36x15 cm, 5-6 animals) at 21-23~ and 12:12 h light regime and had free access to standard vivarium chow and water. A Litron Professional Co. PC/AT-286 computer (Singapore) with an EGA color monitor (230 V, 50 Hz, 0.4 A, Taiwan) was used as a source of radiation (Fig. 1). A text file was on the monitor during irradiation (1 h during a 5-day period). Control rats were subjected to the same manipulations without irradiation. The doses of PCM radiation components were measured as previously [2].

Effects of Mobile Phones on Oxidant/Antioxidant Balance in Cornea and Lens of Rats

“…A personal computer (PC) is standard equipment for many people in industrialized societies, and its use is growing. A PC user is exposed to an electromagnetic field (EMF), visible and ultraviolet light, radio-range waves, and extremely low frequency (50 Hz) fields (ELF) [2]. Preliminary experiments showed that radiation from a monitor can produce potentially hazardous biological effects [2].…”

“…Experimental studies have shown that ELF-EMFs may interfere with chemical reactions involving free radical production [12-14]. Moreover, some researchers have reported that PC monitor use is associated with the free radical process [2,15]. The eye is an exceptional organ because of its continuous exposure to environmental chemicals, radiation, and atmospheric oxygen.…”