Effect of radiation injury on the growing face

Nwoku, Alagumba L.; Koch, H

doi:10.1016/s0301-0503(75)80010-5

Cited by 38 publications

(7 citation statements)

References 16 publications

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“…Skeletal or biological age reflects the level of maturity achieved by the individual 24 . Average skeletal age, then, illustrates the maturation status of normal children compared with their corresponding CA 25 . Hand–wrist radiographs, used in the assessment of biological age 26 , serve as a measure to determine the effects of antineoplastic therapy on skeletal development 27 .…”

Section: Discussionmentioning

confidence: 99%

“…This insult may lead to anodontia, hypodontia, disturbed eruption, deficient mineralization, and/or caries. Injury to the tooth bud from cranial irradiation has also been noted to cause occlusal disharmony and promotes growth retardation 10,11,25,27 . Clinical examination and radiographs have shown delayed development of the teeth, root dwarfism, complete failure of root development and premature apical closure, caries, general growth disturbance, enamel hypoplasia, and microdontia 10,11,28,29 .…”

Section: Discussionmentioning

confidence: 99%

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Correlation of bone age, dental age, and chronological age in survivors of childhood acute lymphoblastic leukaemia

Martin

Rowland³

et al. 2008

Int J Paed Dentistry

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Correlation of bone age, dental age, and chronological age in survivors of childhood acute lymphoblastic leukaemia

Martin

Rowland³

et al. 2008

Int J Paed Dentistry

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“…The difference in pituitary mass may be explained by the effect of secondary radiation, originated from the skull bones. This assumption of bones as a secondary source of radiation was presented by Nwoku and Koch [4] in the study of the impact of radiation therapy on the jaw and teeth in children's with nasopharyngeal carcinoma. Rats in the control group had a uniform growth and constant increase of body mass which was most intensive between the 29 th an 50 th day (Fig.…”

Section: Resultsmentioning

confidence: 95%

Effects of Experimentally Irradiated Pituitary Gland on Some Morphological Parameters of Rats’ Head, Body and Tibia

Milosavljević¹,

Krstić²,

Mitrović³

et al. 2017

RadJ

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Abstract. Studies of X-rays irradiation effects on biological systems are still meaningful and actual. The aim of present work was to examine the effects of pituitary gland irradiation on rats' growth and development, and the impact of pituitary gland protection during cranial irradiation. During the experiment, rats were divided into three groups. Animals in the first group (control group) were not irradiated. In the second and third groups animals received cranial irradiation with 240 kV X-rays at doses of 27.92 Gy (n=10 per group), applied during 8 sessions, in the period from 8 to 63 days of age. In the second group, rats had the pituitary gland protection in the form of a lead plate set below the projection of the pituitary. Animals in the third group were irradiated without the lead plate protection of the pituitary gland. In second group with protected pituitary gland, no significantly harmful effects of radiation were observed in animals. After the cranial irradiation without pituitary gland protection (third group), animals showed significant retardation of physical growth which was manifested in the reduction of pituitary gland mass as in the body and tibial mass and length.

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“…Sensitivity to irradiation has been revealed to be 25% higher in children than adults. 40 In the study by Oehmann et al 41 , the first growth spurts in the orbita was observed at ages between 6 and 8 years (25% increase in volume). Likewise, Imhof et al 30 reported more damage to the orbital growth in children younger than 6 months of age (p< 0.01).…”

Section: Orbital Growth Retardationmentioning

confidence: 93%

Role and Alternative Modalities of External Beam Radiotherapy in the Management of Retinoblastoma

Pehlivan¹

2012

UHOD

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Retinoblastoma (RB) is the most common orbital tumor of childhood. Treatment strategy depends on number, loalization and extent of disease (unilateral vs bilateral) involvement. Currently, significant improvements in treatment and long survival rates have been achieved in management of this tumor group that mandates for search of more sophisticated novel treatment modalities to reduce the risks of treatment related side effects and secondary malignancies. In recent years, both the role and techniques of radiation therapy (RT) have significantly changed in parallel to the improvements in technology. Present review aims to discuss the current treatment modalities in RB, and the role and alternative techniques of RT in the light of recent literature.Keywords: Retinoblastoma, External beam radiotherapy, Toxicity, Chemotherapy, Secondary malignancy ÖZET Retinoblastoma Tedavisinde Eksternal Radyoterapinin Rolü ve Radyoterapi SeçenekleriRetinoblastoma (RB) çocukluk ça¤›n›n en s›k orbital tümörü olup hastal›¤›n tedavisi tümörün say›s›, büyüklü¤ü, lokalizasyonu ve tutulu göz say›s›na göre farkl›l›klar göstermektedir. Uzayan yaflam süresi ile belirginleflen radyoterapi (RT) ve/veya kemoterapiye ba¤-l› yan etkilerle ikincil tümör riskini en aza indirebilecek tedavi alternatiflerinin aranmas›n› zorunlu k›lm›flt›r. Di¤er tedavi seçeneklerinde elde edilen baflar›lar sonucu eksternal RT'nin tedavideki rolündeki de¤iflimin yan› s›ra, RT tekniklerinde de teknolojiye paralel ilerlemeler kaydedilmifltir. Dolay›s›yla güncel derlemede, RB tedavisinde kullan›lan de¤iflik tedavi seçenekleri ve özellikle RT'nin de¤iflen rolü ile tekniklerinin ayr›nt›l› olarak tart›fl›lmas› amaçlanm›flt›r.

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Effect of radiation injury on the growing face

Cited by 38 publications

References 16 publications

Correlation of bone age, dental age, and chronological age in survivors of childhood acute lymphoblastic leukaemia

Correlation of bone age, dental age, and chronological age in survivors of childhood acute lymphoblastic leukaemia

Effects of Experimentally Irradiated Pituitary Gland on Some Morphological Parameters of Rats’ Head, Body and Tibia

Role and Alternative Modalities of External Beam Radiotherapy in the Management of Retinoblastoma

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