Effect of Radical Laparoscopic Surgery and Conventional Open Surgery on Surgical Outcomes, Complications, and Prognosis in Elderly Patients with Bladder Cancer

Abstract

Background. Bladder cancer is a common malignant tumor of the urinary system in the clinic. It has multiple lesions, easy recurrence, easy metastasis, poor prognosis, and high mortality. Objective. The aim of this study is to investigate the impact of laparoscopic radical cystectomy (LRC) and open radical cystectomy (ORC) on the surgical outcome, complications, and prognosis of elderly patients with bladder cancer. Materials and Methods. One hundred elderly bladder cancer patients who underwent surgery in our hospital from June 2019 to June 2021 were selected for the retrospective study and were divided into 50 cases each in the ORC group and the LRC group according to the different surgical methods. The ORC group was treated with ORC, and the LRC group implemented LRC treatment. The differences in surgery, immune function, recent clinical outcomes, and complications between the two groups were observed and compared. Results. The mean operative time, mean intraoperative bleeding, intraoperative and postoperative transfusion rate, and transfusion volume of patients in the LRC group were statistically significant when compared to the ORC group. The differences in the meantime to resume eating, time to get out of bed, mean number of days in hospital after surgery, and the amount of postoperative numbing analgesics used by patients in the LRC group after surgery were statistically significant compared to the ORC group ( P < 0.05 ). There was no statistically significant difference in the comparison of immune function between the two groups before surgery ( P > 0.05 ), while the comparison of CD8+ and B cells 1 week after surgery of the LRC group was significantly better than that of the ORC group ( P < 0.05 ), and the operation time of the LRC group was longer than that of the ORC group ( P < 0.05 ). Statistical analysis of postoperative complications showed that the overall incidence of postoperative complications in the LRC group was significantly lower than that in the ORC group (16.67% vs. 46.67%) ( P < 0.05 ). Conclusion. LRC has less surgical trauma and intraoperative bleeding, faster postoperative recovery, and fewer postoperative complications, providing some reference for clinical surgery for elderly bladder cancer patients.

Effects of Nursing Care for the Treatment of Patients with Bladder Cancer: A Systematic Review and Meta-analysis

“…One of the most frequent malignant tumors of the urinary system, bladder cancer accounts for roughly 3.0 percent of new cases and 2.1 percent of cancer-related fatalities [ 1 ]. High incidence rate, prevalence, recurrence, and mortality of bladder cancer indicate that it is still an unsolved clinical and social problem [ 2 ].…”

Trends of radical cystectomy and comparisons of surgical outcomes among surgical approaches focusing on robot‐assisted radical cystectomy: A Japanese nationwide database study

“…The major types of complications were urinary tract infection and intestinal obstruction, followed by colitis, sepsis, and acute renal failure 5,16 . LRC, MIES‐ RC, and RARC also had several complications at a constant rate 6,17–19 . Interestingly, in the current Japanese nationwide database study, the incidence of complications after RC was shown to be significantly lower in the MIS group than in the ORC group.…”

Comparative analysis of wound healing techniques in postoperative bladder cancer patients

“…Regardless of the method of laparoscopic or conventional open surgery, these incisions are prone to numerous complications bearing potential to impede patient's recuperation and increase the likelihood of adverse health outcomes. Illnesses, dehiscence and delayed healing are not trivial annoyances; rather, they are significant challenges that can extend patients' hospital stays, escalate healthcare expenditures and negatively impact their health 5,6 . These patients are more susceptible to complications due to both intrinsic and extrinsic factors.…”

“…Illnesses, dehiscence and delayed healing are not trivial annoyances; rather, they are significant challenges that can extend patients' hospital stays, escalate healthcare expenditures and negatively impact their health. 5,6 These patients are more susceptible to complications due to both intrinsic and extrinsic factors. Intrinsic factors include nutritional status, age and comorbidities.…”