Effect of refractive status on peripapillary retinal nerve fibre layer thickness: a study by RTVue spectral domain optical coherence tomography

Abstract

We have shown that axial length/refractive status affected the peripapillary RNFL thickness profile measured by RTVue OCT. To make a correct diagnosis for glaucoma, either the axial length-induced magnification effect should corrected by ophthalmologists or the RTVue OCT database should be improved by taking axial length into account.

Clustering of Combined 24-2 and 10-2 Visual Field Grids and Their Relationship With Circumpapillary Retinal Nerve Fiber Layer Thickness

“…Both the SAP sensitivity and cpRNFLT could have been influenced by the high myopia. [37][38][39] Finally, this cross-sectional retrospective study could not evaluate the intersession variability of each VF or cpRNFLT cluster values. To overcome these limitations, future prospective studies with larger sample sizes and strict inclusion criteria are needed.…”

Evaluation of myopia on retinal nerve fiber layer thickness measured by Spectralis optical coherence tomography

“…A study by Oner et al (12) evaluated the RNFL thickness in myopic and emmetropic eyes by SD-OCT and observed that the overall global RNFL thickness of myopic eyes was significantly thinner than that of emmetropic eyes. A study by Table III.…”

Variations of OCT measurements corrected for the magnification effect according to axial length and refractive error in children

“…2 Wang et al 3 revealed that magni¯cation attributable to axial length (AL) and refractive error has minimal impact on measurements of macular and RNFL thickness in 120 children, but they asserted that transverse measurements such as optic disc diameter should be corrected by magni¯cation effect. However, other studies conducted in adults 4,5 and children 6,7 found that AL [4][5][6][7] and refractive error 5,6,8 in°uence the measurements of OCT. The studies mentioned earlier [4][5][6][7][8] referred that AL-related ocular magni¯cation should be taken into account to ensure better accuracy in the measurements made with OCT.…”

“…However, other studies conducted in adults 4,5 and children 6,7 found that AL [4][5][6][7] and refractive error 5,6,8 in°uence the measurements of OCT. The studies mentioned earlier [4][5][6][7][8] referred that AL-related ocular magni¯cation should be taken into account to ensure better accuracy in the measurements made with OCT. Previous studies used time domain OCT (Stratus OCT); however, spectral domain (SD-OCT) such as Cirrus HD-OCT o®ers a higher axial resolution and scanning speed than conventional time-domain techniques.…”