Effect of regular marijuana smoking on platelet function

Golcuk, Yalcin; Golcuk, Burcu; Sözen, Semih

doi:10.1016/j.ajem.2015.02.012

Cited by 4 publications

(3 citation statements)

References 6 publications

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“…75 There have also been case reports describing platelet aggregation as a possible cause of MI. 29,76,77 Hodcroft et al 29 described a young male patient who presented with STEMI shortly after using cannabis. Subsequent angiogram and intravascular ultrasound demonstrated complete thrombus with no underlying atherosclerosis, suggesting that platelet aggregation may have played a central role.…”

Section: Pathogenic Mechanisms Contributing To Cannabis-induced MImentioning

confidence: 99%

A Literature Review of Cannabis and Myocardial Infarction—What Clinicians May Not Be Aware Of

2021

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Increasing legalization and expanding medicinal use have led to a significant rise in global cannabis consumption. With this development, we have seen a growing number of case reports describing adverse cardiovascular events, specifically, cannabis-induced myocardial infarction (MI). However, there are considerable knowledge gaps on this topic among health care providers. This review aims to provide an up-to-date review of the current literature, as well as practical recommendations for clinicians. We also focus on proposed mechanisms implicating cannabis as a risk factor for MI. We performed a CJC Open 3 (2021) 12e21

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Section: Pathogenic Mechanisms Contributing To Cannabis-induced MImentioning

confidence: 99%

A Literature Review of Cannabis and Myocardial Infarction—What Clinicians May Not Be Aware Of

2021

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“…Proposed mechanisms of synthetic cannabinoids associated cerebral and myocardial infarctions include hypotension, arrhythmia, and vasospasm (7). Synthetic cannabinoids is known to a ect cerebral auto-regulation and vascular tone leading to vasoconstriction and acute ischemic stroke (8). Decreased blood supply, vasoconstriction, increased myocardial oxygen consumption, and increased platelet aggregation have been reported to be the possible pathophysiologic mechanisms of cardiovascular e ects of synthetic cannabinoids (9).…”

Section: Discussionmentioning

confidence: 99%

Atypical Cerebral Infarction in a Patient Suspected Ingestion of Synthetic Cannabinoids

Lee

Kim

Lee

et al. 2019

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Background. Synthetic cannabinoids are recreational street drugs with many known adverse e ects. Case presentation. Here we present the case of an atypical cerebral infarction in a patient with a suspected ingestion of synthetic cannabinoids. Conclusion. Although synthetic cannabinoids use is not conventionally associated with stroke, some case reports describe cerebral infarction and myocardial infarction with signi cant synthetic cannabinoids intake. Emergency physicians should know the association of synthetic cannabinoids with seizures, myocardial infarction, and now possibly ischemic stroke.

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“…Platelet activation may also play a key role. [8][9][10] We presented the case of a 26-year-old gentleman who was admitted in hospital with ST elevation myocardial infarction with no thrombosis secondary to cannabis smoking. There is a growing evidence of cannabis causing acute myocardial infarction.…”

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confidence: 99%