2016
DOI: 10.1097/mbp.0000000000000211
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Effect of restoring sinus rhythm in hypertensive patients with atrial fibrillation undergoing electrical cardioversion

Abstract: Restoring SR in hypertensive patients with AF led to a significant increase in their systolic BP (especially at night) and a decrease in their DBP. Hypertensive patients with AF should consequently undergo ambulatory BP monitoring after electrical cardioversion for the purpose of adjusting their antihypertensive treatment.

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Cited by 7 publications
(6 citation statements)
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“…As compared to sinus rhythm, we observed slightly lower systolic BP and slightly higher diastolic BP values in assumed AF, rendering PP values to be dependent on rhythm in this study using intraindividual comparisons. This is in line with our previous findings comparing patients with high likelihood of AF to individuals with low likelihood of AF [ 22 ] and other studies with intraindividual comparisons [ 13 , 14 ]. However, those studies [ 13 , 14 ] did not compare averaged BP values in adjacent episodes of AF and normal rhythm during an ABPM as we did in the current study.…”
Section: Discussionsupporting
confidence: 93%
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“…As compared to sinus rhythm, we observed slightly lower systolic BP and slightly higher diastolic BP values in assumed AF, rendering PP values to be dependent on rhythm in this study using intraindividual comparisons. This is in line with our previous findings comparing patients with high likelihood of AF to individuals with low likelihood of AF [ 22 ] and other studies with intraindividual comparisons [ 13 , 14 ]. However, those studies [ 13 , 14 ] did not compare averaged BP values in adjacent episodes of AF and normal rhythm during an ABPM as we did in the current study.…”
Section: Discussionsupporting
confidence: 93%
“…BP may change during AF, as compared to SR, due to hemodynamic alterations. Some studies comparing BP in AF and in SR in the same subjects before and after direct current cardioversion to restore SR suggest a trend for higher systolic and lower diastolic BP in SR [ 13 16 ]. However, results are inconsistent, study populations were small, and comparisons were not made to intra-arterial BP.…”
Section: Introductionmentioning
confidence: 99%
“…This effect was also noted in our study collective: an overall increase of systolic iBP of 5.6 mmHg was achieved during the 2h-observational-period after having administered Vernakalant. Although conflicting results about how and when exactly restoration of SR can increase BP-values, one theory is the atrial contractility being increased and therefore a greater ejection fraction resulting from the left ventricle 32 . Comparing Vernakalant to other antiarrhythmic agents such as Ibutilide 19 , the slight and immediate effect of BP-increase could be a distinct feature of Vernakalant and not just related to the cardioversion itself.…”
Section: Discussionmentioning
confidence: 99%
“…A decrease in diastolic BP of 5 mm Hg and, in line with our results, an increase in systolic BP of 4‐5 mm Hg following cardioversion were observed. Another study by Maselli et al included 54 hypertensive patients with persistent AF undergoing DC cardioversion. BP was evaluated with ambulatory BP on the day before and about a month after cardioversion.…”
Section: Discussionmentioning
confidence: 99%