Effect of Riboflavin and Choline Deficiencies on Water Metabolism in Rats

Body composition of rats in B-vitamin deficiencies

“…No appreciable deviation from normal water concentration was noted in our vitamin-or calorie-deficient rats. This constancy of water content does not preclude the possibility of a temporary water retention and a delayed diuretic response after a water load in the above recorded nutritional disorders (Guggenheim, 1954a(Guggenheim, , 1954bGuggenheim & Diamant, 1955).…”

“…Increased protein content has been found in livers of rats treated with cortisone (Silber & Porter, 1953; Clark & Pesch, 1956). Evidence of involvement of the adrenals in deficiencies of pyridoxine, riboflavin and pantothenic acid has accumulated during recent years (Morgan, 1951; Ershoff, 1952;Forker & Morgan, 1954; Guggenheim, 1954a; Guggenheim & Diamant, 1955 ;Eisenstein, 1957). The compositions of liver and carcass of adrenalectomized and of cortisone-treated rats were therefore studied for comparison.…”

Effect of Choline on the Hypertension of Rats Induced by High Salt Diet

“…Guggenheim (7) reported that the vasopressin-inactivating ability of rat liver was reduced by choline deficiency.…”