Effect of roflumilast on cytokines levels in patients with Chronic Obstructive Pulmonary Disease

Ostrovskyy, Мykola; Savelikhina, Iryna; Ostrovska, Kseniia; Varunkiv, Oleksandr; Kulynych-Miskiv, Mariana; Korzh, Galyna; Shvets, Kostiantyn; Korzh, Nadiia

doi:10.1183/13993003.congress-2021.pa558

Cited by 1 publication

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The absolute power spectral density (PSD) was used as a quantitative parameter of the electroencephalogram. The spectral analysis of EEG was performed using the fast Fourier transform algorithm to calculate the PSD in standard ranges of physiological frequencies of the main brain rhythms: alpha, beta, theta, and delta [2,20]. Licensed software of the Neuroscope-416 computer electroencephalograph was used for EEG registration and processing.…”

Section: Methodsmentioning

confidence: 99%

“…An open type spirographic complex Spiro-Spectrum (KhAI-Medika, Ukraine) was used in the study. The basic requirements for spirographic examinations [2,21] were observed. Calculation of spirographic indicators and their normative values was carried out using the software Spirokom-Standard.…”

Section: Methodsmentioning

confidence: 99%

“…-Tiff no Index (FEV1/FVC, %). These indicators are diagnostic criteria for bronchial obstruction (BO) and are used to determine the severity of BO [2].…”

Section: Methodsmentioning

confidence: 99%

“…Bronchial asthma (BA) is one of the most common chronic inflammatory diseases of the respiratory tract (predominantly allergic), and its main symptom is breathlessness due to narrowing of the bronchial lumen resulting in chronic airflow limitation and bronchial mucosal edema. Asthma is incurable, but treatment can slow the progression of the disease [1,2,3]. Currently, the basis of asthma treatment is pharmacological agents, which allow to achieve a high level of disease control.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Psychosomatic Mechanisms of Regulation of External Respiration Function in Children With Bronchial Asthma When Listening to Audio Signals of Various Component Composition

Kalashnikova,

Naida,

Didkovskyi

et al. 2023

Neonatol. hìr. perinat. med.

View full text Add to dashboard Cite

In the treatment of bronchial asthma (BA), an integrated approach is used that includes both drugs and alternative methodsthat infl uence the psycho- emotional state of the patient. In this regard, one of the most powerful methods of psycho- emotional infl uence on a person is musical infl uence.The aim of the research is to study the eff ectiveness of infl uence of audio signals of diff erent amplitude- frequency range on the central mechanisms of regulation of ventilatory capacity of bronchi of patients with asthma.Material and methods. Twenty-fi ve children between the ages of 9 and 14 with clinically diagnosed BA participated in thestudy. Three melodies with diff erent component composition were used. Their amplitude- frequency characteristics were analyzed using the Matlab environment. The sound energy fraction of the studied musical compositions in one-third octave frequency bands throughout the duration of the audio signal was calculated. Statistical processing of the data was performed using IBM SPSS Statistics software.Results. The results of the study indicate that the most eff ective musical infl uence is provided by the audio excerpt from The Magic Flute by W. A. Mozart. It was found that the main spirographic indicators of bronchopulmonary obstruction increase under the infl uence of music, and correspondingly there are changes in the integral characteristics of bioelectrical activity of the brain.Conclusion. The results of the study show reliable normalization of spirography indicators in children with bronchial asthmaunder the infl uence of selected musical melodies of a certain frequency. Eff ectiveness of sound infl uence on central regulation mechanisms of bronchial ventilatory capacity can be used for preventive and therapeutic purposes.

show abstract

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

“…-Tiff no Index (FEV1/FVC, %). These indicators are diagnostic criteria for bronchial obstruction (BO) and are used to determine the severity of BO [2].…”

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations