Given the deep oil reservoirs in the Yanchang Formation in the western region of Yanchang Oilfield, the research on drilling and completion technologies for long open-hole horizontal wells is carried out because of the problems such as high drag and torque, difficult trajectory control, borehole cleaning, cementing quality, and many downhole accidents during drilling. From the perspective of drilling and completion, we have developed trajectory control, wellbore stabilization, borehole cleaning, and cementing completion technology for long open-hole horizontal wells. This technology achieved good results in WP-H47 well: Compared with the horizontal wells of the same period, the downhole complications during drilling and completion were significantly reduced and the average drilling cycle was shortened by 6.5 days. This technology helped build the longest open-hole horizontal well in the Yanchang Oilfield, which is a reference for the development of long open-hole horizontal wells in later years.