Effect of rumen-protected methionine supplementation to beef cows during the periconception period on performance of cows, calves, and subsequent offspring

Silva, G.M.; Chalk, C.D.; Ranches, Juliana; Schulmeister, Tessa M; Henry, Darren D; DiLorenzo, Nicolás; Arthington, J. D.; Moriel, Philipe; Lancaster, P. A.

doi:10.1016/j.animal.2020.100055

Cited by 24 publications

(26 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In the present study, we observed a positive effect of maternal AA supply to pre-calving cows on calf growth performance, similar to previous studies on feeding RPM to close-up cows ( 29 ), but not in other ( 64 ). The results from this study may be due to alterations in the uteroplacental transport of essential and non-essential AAs and glucose and mechanistic target of rapamycin (mTOR) signaling, which has been indicated earlier ( 41 ).…”

Section: Discussionsupporting

confidence: 92%

Maternal Supply of Ruminally-Protected Lysine and Methionine During Close-Up Period Enhances Immunity and Growth Rate of Neonatal Calves

Wang

Elsaadawy

et al. 2021

Front. Vet. Sci.

View full text Add to dashboard Cite

The objective of this study was to evaluate the effect of supplying ruminally-protected lysine (RPL), methionine (RPM), or the two in combination (RPML) to transition dairy cows on the immunity and performance of their offspring. Eighty heifer calves (n = 20 calves per group) were assigned to four treatments based on their dam diet; basal diet (CON), a basal diet with lysine [RPL, 0.33% of dry matter (DM)], a basal diet with methionine (RPM, 0.16% DM), or with the combination (RPML). Calves were fed colostrum from their dams within 2 h of birth. Calves were then fed milk only (d 2–22), a combination of milk and milk replacer (d 23–25), and milk replacer (d 25–60). Starter feed was fed to the calves twice daily after liquid feeding. Calves blood samples were collected after calving on 0, 12, 24, and 48 h and 5 and 7 d after birth. Data were analyzed by SAS software v9.4. Providing ruminally-protected amino acids (RPAA) to transition cows improved colostrum quality compared to the CON (Brix; P < 0.01). Serum total protein concentrations were higher in calves from supplemented cows than in calves from unsupplemented cows (P < 0.01). Calves born to dams in the RPM, RPL, and RPML groups had higher plasma immunoglobulin G (IgG) concentrations 0, 12, 24, and 48 h and 7 d after birth than those born to dams in the CON group (P < 0.05). The percentage of calves with adequate passive immunity transfer was increased with RPM and RPL or the two in combination (P < 0.01). However, there was no difference in the percentage of calves with adequate passive immunity transfer between the RPM and RPL groups (P = 0.21). Calves from cows that receive supplemental RPAA have a greater average daily gain (ADG) than those born to cows in the CON group (P < 0.01). These results indicate that maternal supplementation with RPM or RPL or the two in combination during the periparturient period could be an alternative strategy to improve the performance of calves, especially in accelerated growth programs in calves.

show abstract

Section: Discussionsupporting

confidence: 92%

Maternal Supply of Ruminally-Protected Lysine and Methionine During Close-Up Period Enhances Immunity and Growth Rate of Neonatal Calves

Wang

Elsaadawy

et al. 2021

Front. Vet. Sci.

View full text Add to dashboard Cite

show abstract

“…Brangus-Angus cows from UF/Ona were fed one of two diets from days − 30 to + 90 relative to the beginning of the breeding season. The diets consisted of (i) a control diet based on limpograss hay ( Hemarthria altissima ) with the supplementation of molasses and urea (22 % crude protein, 1.7 kg per head per day), or (ii) a methionine-rich diet equal to the control diet but supplemented with 10 g per head per day of MetaSmart Liquid (Adisseo, Alpharetta, GA) providing 3.7 g per head per day of rumen-protected methionine [ 50 ]. Longissimus dorsi muscle samples were collected from a total of 20 bull calves, 10 animals per maternal diet, at 1 month of age.…”

Section: Methodsmentioning

confidence: 99%

Maternal methionine supplementation during gestation alters alternative splicing and DNA methylation in bovine skeletal muscle

et al. 2021

View full text Add to dashboard Cite

Background The evaluation of alternative splicing, including differential isoform expression and differential exon usage, can provide some insights on the transcriptional changes that occur in response to environmental perturbations. Maternal nutrition is considered a major intrauterine regulator of fetal developmental programming. The objective of this study was to assess potential changes in splicing events in the longissimus dorsi muscle of beef calves gestated under control or methionine-rich diets. RNA sequencing and whole-genome bisulfite sequencing were used to evaluate muscle transcriptome and methylome, respectively. Results Alternative splicing patterns were significantly altered by maternal methionine supplementation. Most of the altered genes were directly implicated in muscle development, muscle physiology, ATP activities, RNA splicing and DNA methylation, among other functions. Interestingly, there was a significant association between DNA methylation and differential exon usage. Indeed, among the set of genes that showed differential exon usage, significant differences in methylation level were detected between significant and non-significant exons, and between contiguous and non-contiguous introns to significant exons. Conclusions Overall, our findings provide evidence that a prenatal diet rich in methyl donors can significantly alter the offspring transcriptome, including changes in isoform expression and exon usage, and some of these changes are mediated by changes in DNA methylation.

show abstract

“…Estas adaptações fisiológicas determinam a capacidade produtiva da progênie quando desafiados na vida adulta. Por exemplo, Silva et al (2021) observaram que a suplementação 115 dias antes da concepção melhorou a digestibilidade aparente da fibra do trato digestório e a eficiência alimentar de bezerros de corte com programação fetal. No mesmo experimento, os autores observaram que bezerros cujas mães receberam metionina tenderam a ter maior digestibilidade aparente de FDN e FDA no trato digestório total e menor concentração de glicose no sangue em relação aos bezerros de mães controle e sulementadas com farinha de peixe.…”

Section: Implicações No Desempenho Da Progênieunclassified

Programação fetal e as consequências no desenvolvimento da progênie – uma revisão

Klein

Adams

Filho

et al. 2021

RSD

View full text Add to dashboard Cite

O objetivo deste trabalho foi, através de uma revisão de literatura, identificar as principais alterações fisiológicas e comportamentais causadas pela programação fetal que afetam a saúde e o desempenho da progênie na vida pós-natal. Dentre os inúmeros fatores que alteram a formação fetal, a nutrição materna na gestação tem sido fortemente referenciada nas pesquisas recentes. A nutrição materna na gestação pode alterar de inúmeras formas a formação fetal, de forma que o feto se adapte o mais rapidamente possível ao ambiente uterino, sendo essas mudanças perceptíveis durante a vida adulta da progênie. De modo geral, a literatura sugere que a restrição materna na gestação pode promover mudanças fisiológicas e funcionais nos órgãos e tecidos do feto, preparando o organismo para sobreviver em ambientes desafiadores também na vida pós-natal. Além disso, indivíduos que experimentaram ambientes restritos durante a formação fetal, apresentam maior procura por alimento e comportamentos psicossociais alterados, tais como reações de medo, isolamento e reatividade. A maior eficiência produtiva e consequentemente menor idade de abate da progênie tem sido associada a melhor nutrição materna durante a gestação, uma vez que esses indivíduos possuem formação fetal adequada e, portanto, maior capacidade metabólica dos nutrientes em sistemas intensivos de produção que almejam o máximo desempenho animal.

show abstract

Effect of rumen-protected methionine supplementation to beef cows during the periconception period on performance of cows, calves, and subsequent offspring

Cited by 24 publications

References 30 publications

Maternal Supply of Ruminally-Protected Lysine and Methionine During Close-Up Period Enhances Immunity and Growth Rate of Neonatal Calves

Maternal Supply of Ruminally-Protected Lysine and Methionine During Close-Up Period Enhances Immunity and Growth Rate of Neonatal Calves

Maternal methionine supplementation during gestation alters alternative splicing and DNA methylation in bovine skeletal muscle

Programação fetal e as consequências no desenvolvimento da progênie – uma revisão

Contact Info

Product

Resources

About