Effect of Sangrovit on Performance and Morphology of Small Intestine and Immune Response of Broilers

Abstract

This study was designed to investigate the effects of Sangrovit on performance, small intestinal morphology, and immune response of 300 commercial hybrid broilers, Ross 308. The study was conducted in the Agricultural Research Station of Islamic Azad University, Varamin, in the spring 2010 for 42 days. The broilers were kept in a completely randomized design with 3 treatments, 4 replicates, 12 experimental units each containing 25 broilers. Treatments used in this experiment included controls, 0.05 % and 0.1 % Sangrovit of total ration. The test results showed no significant difference between different treatments during the breeding period on feed intake, feed conversion, and small intestinal morphology. However, treatments containing 0.1% Sangrovit showed significant differences on weight gain in the early rounds between the other treatments (P<0.05). Statistically, these differences were not significant during the breeding period. Regarding the effects of different treatments on the carcass components, the diet containing 0.05% Sangrovit could significantly increase the weight of the thigh (P<0.05) than the other diets. In this treatment, the mean serum antibody titers against Newcastle disease by HI method showed significant differences at 35 and 42 days of the breeding period (P<0.05). Based on the results of this experiment, Sangrovit can obtain the desired results in improving immune system, performance and carcass yield.

Effects of different levels of sanguinarine on antioxidant indices, immunological responses, ileal microbial counts and jejunal morphology of laying hens fed diets with different levels of crude protein

“…Our findings were in accordance with those of Karimi et al. (), who showed that the intake of 7.5 mg sanguinarine/kg of diet (500 g Sangrovit/kg) improved the antibody titre in broiler chicks. However, Mirzadeh et al.…”

Influence of sanguinarine-based phytobiotic supplementation on post necrotic enteritis challenge recovery

“…Dietary supplementation of quaternary benzophenanthridinze and protopine alkaloids combination has been related to increasing of villi height, villi width, villus/crypt ratio, and surface area of jejunum in broilers [53]. Conversely, Karimi et al [16], and Zhang et al [54], reported that dietary supplementation with sanguinarine had no effect on intestinal histology which is more in line with our data. Comparing ileum photomicrograph of broilers under NE challenge and phytobiotic supplementation represented a slight improvement in villus structure.…”

“…In the current trial, the supplementation of sanguinarine-based phytobiotic did not affect performance parameters in the post-NE induced infection period. Others reported an increase in body weight, enhanced performance, and carcass yield [11,16]. Recently El-Sheikh et al [48], reported an improvement in the clinical signs of NE in birds under C. perfringens and sanguinarine phytobiotic supplementation, including intestinal lesion scores.…”

“…The use of sanguinarine-like alkaloid supplements in poultry feed has a positive influence on growth performance, anti-inflammatory properties, and antimicrobial activity against enteric pathogens [11,12,13,14,15]. Karimi et al [16], investigated the impact of commercial sanguinarine-based phytobiotic on broiler performance, small intestine morphology, and immune function. The results indicated that feed intake and small intestinal morphology were not significantly altered.…”

Tolerance Study for Standardized &lt;i&gt;Macleaya cordata&lt;/i&gt; Extract Added to Chicken Layer Diet

“…Ross 308 broilers fed MCEP at 500 and 1000 mg/kg feed (0.05% and 0.1% of the diet, respectively) also did not significantly increase feed intake, FCR or small intestinal morphology during the entire 42 day study period [7]. However, transient increases in LW and cumulative MCEP effects were found [8] when MCEP was consumed at 50 mg/kg feed from D1 -D21 and MCEP at 25 mg/kg feed from D22 -D42 by male Cobb broiler chicks, corresponding to increased feed intake.…”