Effect of SARS-CoV-2 infection on out-of-hospital cardiac arrest outcomes – systematic review and meta-analysis

Abstract

Introduction andObjective. The COVID-19 pandemic caused by the SARS-CoV-2 virus has recently presented the world with an unprecedented challenge. The purpose of this systematic review and meta-analysis is to investigate the relationship between SARS-CoV-2 infection and out-of-hospital cardiac arrest (OHCA) by comparing data from infected and non-infected individuals. The study adds to our understanding of the broader effects of the pandemic on public health and emergency care by examining the influence of COVID-19 on OHCA. Materials and method. A comprehensive systematic literature search was performed using PubMed, EMBASE, Scopus, Web of Science, the Cochrane Library and Google Scholar from 1 January 2020 -24 May 2023. Incidence rates and odds ratios (ORs) or mean differences (MDs) with 95% confidence intervals (CIs) for risk factors were recorded from individual studies, and random-effects inverse variance modelling used to generate pooled estimates. Results. Six studies, involving 5,523 patients, met the criteria for inclusion in the meta-analysis. Survival to hospital admission, defined as admission to the emergency department with sustained return of spontaneous circulation (ROSC), among patients with and without on-going infection was 12.2% and 20.1%, respectively (p=0.09). Survival to hospital discharge/30-day survival rate was 0.8% vs. 6.2% (p<0.001). Two studies reported survival to hospital discharge in good neurological condition; however, the difference was not statistically significant (2.1% vs. 1.8%; p=0.37). Conclusions. Compared to the non-infected patients, the ongoing SARS-CoV-2 infection was associated with worse OHCA outcomes.

The impact of the COVID-19 pandemic on airway management with supraglottic airway devices among out-of-hospital cardiac arrests: a systematic review and meta-analysis

“…The COVID-19 pandemic leads to deaths and has significant effects on other health indicators, particularly in emergencies. Overburdened healthcare systems have had an impact on out-of-hospital cardiac arrest (OHCA) [4,5]. There has been an increase in OHCA in recent years, which is believed to be linked to COVID-19-related illnesses, patients' difficulty getting preventive or general medical treatment, and their unwillingness to seek care due to the risk of COVID-19 transmission in hospitals [6,7].…”

Knowledge, attitudes, and practices towards COVID-19 and COVID-19 vaccines among Obstetrician-Gynaecologists

“…In December 2019, a new coronavirus SARS-CoV-2 was identified in Wuhan, China. This virus spread rapidly and led to a global pandemic [1][2][3][4]. On 11 February 2020, the World Health Organization (WHO) named the disease 'Coronavirus Disease 2019' (COVID-19) [5][6][7].…”

Implementing double sequential defibrillation in accordance with the 2023 ILCOR consensus

“…It is important to note that COVID-19 infection may be linked to ventricular tachycardia or ventricular fibrillation storm, both during the acute and convalescent stages of the infection -so there may be more and more such rhythms for the use of DSED, even as cardiovascular complications of the COVID-19 [3]. We have plenty of evidence on how the pandemic has affected, for example, cardiac arrest or arrhythmias, and we know that this evidence has rather poor prognostic effects for the future [4][5][6][7][8]. Additional investigation into the use of DSED and proper equipment preparation is www.journals.viamedica.pl essential.…”