Effect of A118G (rs1799971) single‐nucleotide polymorphism of the μ‐opioid receptor OPRM1 gene on intraoperative remifentanil requirements in Japanese women undergoing laparoscopic gynecological surgery
Ruying Zou,
Daisuke Nishizawa,
Rie Inoue
et al.
Abstract:AimAbundant data are available on the effect of the A118G (rs1799971) single‐nucleotide polymorphism (SNP) of the μ‐opioid receptor OPRM1 gene on morphine and fentanyl requirements for pain control. However, data on the effect of this SNP on intraoperative remifentanil requirements remain limited. We investigated the effect of this SNP on intraoperative remifentanil requirements.MethodsWe investigated 333 Japanese women, aged 21–69 years, who underwent laparoscopic gynecological surgery for benign gynecologica… Show more
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