This study evaluated the germination of Cinchona spp. seeds under controlled environmental conditions within a geodesic dome equipped with photovoltaic energy. The main objective was to assess how stable temperature and humidity, along with potassium nitrate (KNO3) and specific LED light treatments, affect the germination rate and plant growth. The results indicate that Cinchona spp. seeds germinate effectively inside the dome, even under temperature and humidity conditions that differ from their natural habitat. Among the evaluated conditions, the treatment with 1000 ppm of KNO3 and white LED light (LM 1000 ppm) showed the highest germination rate, achieving 72.5% with an average of 1.5 seeds germinated per day. Agronomic evaluations showed that this treatment also led to superior growth metrics, including an average plant height of 2.1 cm, an average leaf count of 3.6, and a dry weight of 0.0013 g. This research highlights the potential of controlled environments, such as geodesic domes, to optimize germination and early growth in endangered plant species. The combination of environmental control with KNO3 treatments offers a valuable approach to enhancing the propagation of Cinchona spp., providing practical implications for conservation and reforestation efforts. This work provides a foundation for further studies on optimizing germination and growth conditions for other native and endangered species in controlled environments.