Effect of selenium and vitamin E supplementation on the metabolic status of dairy goats and respective goat kids in the peripartum period

Barcelos, Brenda; Gomes, Viviani; Vidal, Ana Maria Centola; Júnior, José Esler de Freitas; Araújo, Maria Leonor Garcia Melo Lopes de; Alba, Henry Daniel Ruiz; Netto, Arlindo Saran

doi:10.1007/s11250-021-03034-1

Cited by 3 publications

(3 citation statements)

References 60 publications

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“…Separate studies have established the influence of trace elements on the metabolic status of the body, including changes in blood composition and the flow of biochemical reactions (Barcelos et al, 2022;Silva et al, 2022). This is explained by the fact that, in most cases, metal ions enter the active center of a number of enzymes that catalyze biochemical processes.…”

Section: Discussionmentioning

confidence: 99%

“…Selenium is one of the most effective substances with a powerful antioxidant effect (Kiełczykowska et al, 2018). Selenium compounds in the body can stimulate the synthesis of reduced glutathione in vivo and play a functional role in increasing the antioxidant capacity and the body's immune response to increased oxidative stress (Barcelos et al, 2022). For example, the antioxidant properties of selenium include the activation of glutathione peroxidase, one of the key cytosolic enzymes of the glutathione defense link, capable of reducing the bactericidal activity of neutrophils (Bai et al, 2017;Giménez et al, 2021).…”

Section: Discussionmentioning

confidence: 99%

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Antioxidant system of the body of young Ukrainian beef cattle under the action of microelements

Mylostуva,

Farafonov,

Puzniak

et al. 2023

Regul. Mech. Biosyst.

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Active forms of oxygen are formed in the course of the organism's vital activity in biochemical reactions. These forms, when the pro/antioxidant balance is disturbed, trigger a cascade of lipid peroxidation, which can be the cause of the development of various pathological conditions. To prevent the negative influence of lipid peroxidation products in the body, a powerful antioxidant system is activated. This system consists of an enzymatic and a non-enzymatic link. An important aspect of the normal functioning of this system is the provision of the body with important trace elements. A number of minerals are included in the active center of antioxidant enzymes or have an effect on the reactions of non-enzymatic antioxidants. Research was conducted on fattening bulls of the Ukrainian meat breed. During the monitoring of microelements in feed, it was found that the vast majority of farm feed was deficient in copper, selenium and manganese and for this reason the animals consumed an insufficient amount of these minerals. These data were confirmed by the low content of these trace elements in blood serum. The addition of inorganic salts of microelements to the basic diet led to an increase in the concentration of copper, manganese and selenium in the blood serum by 20.5%, 37.3% and 23.9%. The study of the content of lipid peroxidation products showed that during the 30 days of the experiment, the level of lipid hydroperoxide increased by 25.5%, diene conjugates by 22.8%, and malonic dialdehyde by 22.0%. This indicates that against the background of increased age-related metabolism in the body of young animals, the oxidation-reduction reactions that are a predictor of the start of peroxidation processes increase. It was also noted that with a deficiency of certain trace elements, the activity of both the enzymatic and non-enzymatic links of the antioxidant system was reduced. Thus, in 30 days, the level of catalase, superoxide dismutase, and glutathione peroxidase decreased by 9.4%, 15.3%, and 13.0%, respectively. During this time, the content of tocopherol and ceruloplasmin decreased by 16.8% and 9.8%. Additives also had a positive effect on the activity of the antioxidant system by increasing its components. Additives of trace elements had different effects on the activity of antioxidant enzymes. The greatest effect on the level of catalase and superoxide dismutase was observed when copper salts were added, when the increase of these enzymes was noted by 1.11 and 1.23 times, respectively. Accordingly, the level of glutathione peroxidase was the highest in animals that received additional selenium – 1.21 times. The addition of copper also had the greatest biological effect on the important non-enzymatic component of antioxidant protection – ceruloplasmin. Its level increased by 1.24 times under the action of copper sulfate. The level of tocopherol was higher under the action of manganese, when its concentration was 1.11 times higher than the control. Against this background, there was a decrease in the products of lipid peroxidation: lipid hydroperoxides – 1.19 times under the action of selenium; diene conjugates – by 1.22 times and malonіс dialdehyde – by 1.11 times under the influence of copper and manganese compounds, respectively.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Antioxidant system of the body of young Ukrainian beef cattle under the action of microelements

Mylostуva,

Farafonov,

Puzniak

et al. 2023

Regul. Mech. Biosyst.

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“…Selenium has a biological action close to Vit. E at the cellular level and is one of the basic constituents of glutathione peroxidase, which is an indicator of oxidative stress and responsible for removal of hydrogen peroxide and hydroperoxide from fats [9]. Selenium components as organic and inorganic selenium in the diet of lambs have effective roles in improving the immune and nervous systems [3].…”

Section: Introductionmentioning

confidence: 99%

Correlations between Sodium Selenite and Vitamin E with Serum Macro-Minerals in Male Lambs

2022

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The effects of selenium and vitamin E (Vit. E) were evaluated on the macro-elements and their relationships were also surveyed. Lambs were divided into 4 groups of control, Vit. E, sodium selenite and sodium selenite/Vit. E (Se/E). Sodium selenite (0.1 mg.kg−1) and Vit. E (8 mg.kg−1) were administered. The mean blood selenium was high in sodium selenite. Selenium only in the Se groups was continuously increased. The lowest and highest blood selenium were in Vit. E and sodium selenite, respectively. The mean serum macro-minerals were within the normal range. The trend of calcium and magnesium in the selenium groups was to increase until day 60, but phosphorus was to decline. The lowest and highest calcium were observed in the control and sodium selenite groups, for magnesium in Vit. E and control groups, and for inorganic phosphorus were in the control group, respectively. The comparison of minerals showed that selenium had a significant increase from day 14 to 90 in sodium selenite. Selenium showed the most positive relationships with calcium and inorganic phosphorus in Vit. E and sodium selenite. Overall, selenium was correlated with macro-minerals on day 90 and overall sampling times were with calcium. In conclusion, administration of selenium with Vit. E increased selenium, which was more observed in the sodium selenite group. Sodium selenite alone or with Vit. E had no effect on the macro-minerals. The least correlation was observed between selenium and macro-minerals in the Se/E administration. The correlation between macro-minerals was positive. It was concluded that the effect of sodium selenite on treatment and prevention of selenium deficiency was more effective than other groups. Vit. E per selenium did not change the selenium concentration. Selenium administration was associated with an increase in calcium level and their co-administration is recommended.

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Milk yield, composition and immune status of dairy goats and respective goat kids fed diets with selenium and vitamin E supplementation

Barcelos

Gomes

Vidal

et al. 2023

Small Ruminant Research

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Effect of selenium and vitamin E supplementation on the metabolic status of dairy goats and respective goat kids in the peripartum period

Cited by 3 publications

References 60 publications

Antioxidant system of the body of young Ukrainian beef cattle under the action of microelements

Antioxidant system of the body of young Ukrainian beef cattle under the action of microelements

Correlations between Sodium Selenite and Vitamin E with Serum Macro-Minerals in Male Lambs

Milk yield, composition and immune status of dairy goats and respective goat kids fed diets with selenium and vitamin E supplementation

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