Effect of Serum Vitamin D Levels on Cardiovascular Mortality and Cardiovascular Disease Risk

Abstract

Vitamin D deficiency is prevalent across all geographic areas, age groups, and seasons and is increasing in incidence. Vitamin D receptors have been found to be present in almost every body cell and tissue. Clinical research has alluded to a preventive effect of vitamin D supplementation on cardiovascular disorders such as myocardial infarction, hypertension, and dyslipidemia. Furthermore, a low serum vitamin D level has been associated with an increased risk for cardiovascular disease. This article examines the association between serum vitamin D levels and cardiovascular disease mortality and risk.

Assessment of vitamin D and its association with cardiovascular disease risk factors in an adult migrant population: an audit of patient records at a Community Health Centre in Kensington, Melbourne, Australia

“…The prevalence of CHD in Australia has been reported to be 3.0% (males 4.4%, females 2.3%) [ 37 ] and the mean 10-year Framingham cardiovascular risk to be 6.3% [ 38 ]. Observational studies have suggested an association exists between vitamin D status and cardiovascular disease outcomes [ 39 ]. A meta-analysis in 2012 found a linear inverse association between vitamin D (ranging from 20–60 nmol/L) and cardiovascular disease.…”