Milk production is essential for optimal feeding of infants. The most common lactogenic drugs are dopamine 2 antagonists, oxytocin, recombinant bovine somatotropin (rBST), thyrotropin releasing hormone (TRH) and estrogenic drugs. However, many medicinal plants possess lactogenic effects in humans and animals. The current review focused on medicinal plants with lactogenic effect as natural sources of galactogogues characterized by efficacy and safety.