Effect of shear viscosity on the preparation of sphere-like silk fibroin microparticles by electrospraying

Kim, Moo Kon; Lee, Jeong Yun; Oh, Han-Jin; Song, Dae Woong; Kwak, Hyo Won; Yun, Haesung; Um, In Chul; Park, Young Hwan; Lee, Ki Hoon

doi:10.1016/j.ijbiomac.2015.05.040

Cited by 35 publications

(19 citation statements)

References 38 publications

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“…The size of the resulting particles is influenced by the type of grinding miller and the aperture of the vibratory sieve shaker [42,43]. Various other methods for SF micro- and nanoparticle preparation have been reported, including desolvation [44], spray drying [45], laminar jet break-up [46], capillary microdot [47], and electrospray techniques [48]. …”

Section: Structure Design Of Silk Fibroin-based Biomaterialsmentioning

confidence: 99%

A Review of Structure Construction of Silk Fibroin Biomaterials from Single Structures to Multi-Level Structures

Wang

Wei

et al. 2017

IJMS

404

241

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The biological performance of artificial biomaterials is closely related to their structure characteristics. Cell adhesion, migration, proliferation, and differentiation are all strongly affected by the different scale structures of biomaterials. Silk fibroin (SF), extracted mainly from silkworms, has become a popular biomaterial due to its excellent biocompatibility, exceptional mechanical properties, tunable degradation, ease of processing, and sufficient supply. As a material with excellent processability, SF can be processed into various forms with different structures, including particulate, fiber, film, and three-dimensional (3D) porous scaffolds. This review discusses and summarizes the various constructions of SF-based materials, from single structures to multi-level structures, and their applications. In combination with single structures, new techniques for creating special multi-level structures of SF-based materials, such as micropatterning and 3D-printing, are also briefly addressed.

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Section: Structure Design Of Silk Fibroin-based Biomaterialsmentioning

confidence: 99%

A Review of Structure Construction of Silk Fibroin Biomaterials from Single Structures to Multi-Level Structures

Wang

Wei

et al. 2017

IJMS

404

241

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“…The basic principles of the ES technique are similar to those from ESP to design the filament. Depending on the concentration of the polymer used during the ES process, particles or fibers can be obtained [54]. ES is useful to design nano or MPs.…”

Section: Experimental Parameters That Influence Es During the Design mentioning

confidence: 99%

Fabrication of Polymeric Microparticles by Electrospray: The Impact of Experimental Parameters

Morais

Vieira

Afewerki

et al. 2020

JFB

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Microparticles (MPs) with controlled morphologies and sizes have been investigated by several researchers due to their importance in pharmaceutical, ceramic, cosmetic, and food industries to just name a few. In particular, the electrospray (ES) technique has been shown to be a viable alternative for the development of single particles with different dimensions, multiple layers, and varied morphologies. In order to adjust these properties, it is necessary to optimize different experimental parameters, such as polymer solvent, voltage, flow rate (FR), type of collectors, and distance between the collector and needle tip, which will all be highlighted in this review. Moreover, the influence and contributions of each of these parameters on the design and fabrication of polymeric MPs are described. In addition, the most common configurations of ES systems for this purpose are discussed, for instance, the main configuration of an ES system with monoaxial, coaxial, triaxial, and multi-capillary delivery. Finally, the main types of collectors employed, types of synthesized MPs and their applications specifically in the pharmaceutical and biomedical fields will be emphasized. To date, ES is a promising and versatile technology with numerous excellent applications in the pharmaceutical and biomaterials field and such MPs generated should be employed for the improved treatment of cancer, healing of bone, and other persistent medical problems.

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“…This can increase the beta-sheet content dramatically [27][28][29][30]. Moreover, SS, in vitro, can further able to selfassemble into small nano-fibrils upon developing, at room temperature for some days, in potassium phosphate buffer [28][29][30][31]. One can structurally compare the obtained SS-fibrils with amyloid fibrils.…”

Section: Artificial Spinning Of Spider Silkmentioning

confidence: 99%

“…Here, the produced films can give secondary and tertiary structure formation of these proteins depending on preparation conditions. Several papers [27][28][29][30] reported that SS-proteins of MA are intrinsically unfolded in aqueous solution. However, if one prepares a SS-film, the proteins rapidly will alter to a spiral arrangement and post-handling of the diaphragms with non-polar solvents such as methyl alcohol can lead to more structural rearrangements of SS-protein.…”

Section: Artificial Spinning Of Spider Silkmentioning

confidence: 99%

Tailored Spider Silk: The Future Solution to Biomaterials

Abdalla¹,

Obaid²,

Al-Marzouki³

et al. 2017

J Material Sci Eng

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Effect of shear viscosity on the preparation of sphere-like silk fibroin microparticles by electrospraying

Cited by 35 publications

References 38 publications

A Review of Structure Construction of Silk Fibroin Biomaterials from Single Structures to Multi-Level Structures

A Review of Structure Construction of Silk Fibroin Biomaterials from Single Structures to Multi-Level Structures

Fabrication of Polymeric Microparticles by Electrospray: The Impact of Experimental Parameters

Tailored Spider Silk: The Future Solution to Biomaterials

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