Effect of shiitake(Lentinus edodes) and maitake(Grifola frondosa) mushrooms on blood pressure and plasma lipids of spontaneously hypertensive rats.

Abstract

To study the effect of Shiitake (Lentinus edodes) and Maitake (Grifola frondosa) on hypertension, spontaneously hypertensive rats (SHR) were fed a diet containing 5% mushroom powder and 0.5 NaCl solution as drinking water for 9 weeks. The dietary mushrooms decreased the blood pressure. The plasma free cholesterol level decreased in Shiitake-fed animals, whereas in Maitake-fed animals the total choles terol level decreased. There was no difference in the plasma triglyceride and phospholipid levels among the experimental groups. Shiitake feeding resulted in a decrease in VLDL-and HDL-cholesterol whereas Maitake feeding caused a decrease in VLDL-cholesterol only. Plasma LDLcholesterol was not affected by dietary mushrooms. The results suggest that dietary mushrooms prevent blood pressure increase in hypertension.

Ganoderma lucidum Polysaccharides and Terpenoids: Profile and Health Benefits

“…Their results clearly showed that the cultured broth had an anti-hepatitis B virus activity in vitro and protected mice from liver damage in vivo. On the other hand, different studies reported the relationship between low plasma cholesterol levels and mushrooms consumption [67][68][69][70]. In animal experiments, Kabir et al [71] investigated the dietary effect of G. lucidum on blood pressure and their results showed a significant reduction of the plasma cholesterol level in animals fed with G. lucidum, and these observations have been reported previously.…”

Ultrastructural Process of Protoplast Fusion BetweenLentinula edodesandCoriolus versicolor

“…L. edodes inhibits the growth of tumor cells, the replication of herpes simplex virus, HIV infection, and blood cholesterol level (Fujii et al, 1978;Hamuro et al , 1980;Sakar et al, 1993;Suzuki et al , 1989 ;Kabir et al , 1987). C.…”

Solid State Characterization of Sodium Eritadenate

“…Another hypocholesterolemic compound of fungal origin is D-eritadenine, 2(R), 3(R)-dihydroxy-4-(9-adenyl)-butanoic acid (Figure 1), found in the shiitake mushroom, Lentinus edodes [2,3]. The shiitake mushroom has been shown to lower the blood cholesterol in both animals and humans [4][5][6], and the cholesterol reducing mechanism of eritadenine has been investigated in several studies on rats [2,3,[7][8][9][10]. The complete hypocholesterolemic mechanism of eritadenine remains to be clarified, but it has been shown that eritadenine accelerates the removal of blood cholesterol, with no indications of the compound inhibiting the biosynthesis of cholesterol [10], unlike the statins [1].…”