Effect of Silicone Oil Components on Corneal Endothelial Passive Permeability and Ion Transport

Characterization of tannery effluent wastewater by proton-induced X-ray emission (PIXE) analysis to investigate their role in water pollution

“…Despite the fact that Si is known to possess a low degree of toxicity, using the water containing increased amount of Si has been reported to cause skin irritation, transient eye irritation, corneal endothelial changes, and retinal toxicity (Green et al 1994).…”

Human and Rabbit Corneal Endothelial Permeability after Different Chemical Forms of Glutathione

“…The fluxes of 14 C-dextran (70,000 daltons) and 3 H-inulin (nominally 5,000 daltons; both from Dupont/NEN, Boston, Mass., USA) were determined from the stromal to endothelial surfaces of the cornea with no mechanical pressure across the cornea [6,21,22]. After a 1-hour equilibration period, the endothelial surface solution was completely replaced by flushing the chamber with an excess volume of solution (flush vs. chamber volume ratio of 10:1) and the effluent discarded; a second replacement was made immediately using a 5:1 volume ratio and this solution was collected and sampled for determination of radioactivity.…”

“…The permeability (!10 -6 cm/s) was calculated as described previously [21,22] based upon the number of paired corneas per test condition. Variations in inulin or dextran permeability between different pairs of corneas reflect the use of different batches of both nonelectrolytes.…”