Effect of smoking on survival and morbidity in patients randomized to medical or surgical therapy in the coronary artery surgery study (CASS): 10-Year follow-up

Cavender, J. B.; Rogers, William J.; Fisher, Lloyd D.; Gersh, Bernard J.; Coggin, C J; Myers, Wayne L.

doi:10.1016/0735-1097(92)90092-2

Cited by 171 publications

(71 citation statements)

References 22 publications

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“…A history of smoking has been reported to be associated with an adverse outcome amongst patients with various manifestations of ischaemic heart disease [12][13][14]. In this survey we found a history of smoking to be an independent risk factor for stroke.…”

Section: Discussionsupporting

confidence: 52%

Factors associated with development of stroke long‐term after myocardial infarction: experiences from the LoWASA trial

Herlitz¹,

Holm²,

Peterson³

et al. 2005

Journal of Internal Medicine

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Objective. To describe factors associated with the development of stroke during long-term follow-up after acute myocardial infarction (AMI) in the LoWASA trial. Patients. Patients who had been hospitalized for AMI were randomized within 42 days to receive either warfarin 1.25 mg plus aspirin 75 mg daily or aspirin 75 mg alone. Design. The study was performed according to the probe design, that is open treatment and blinded end-point evaluation.Setting. The study was performed in 31 hospitals in Sweden. The mean follow-up time was 5.0 years with a range of 1.7-6.7 years. Results. In all, 3300 patients were randomized in the trial, of which 194 (5.9%) developed stroke (4.2% nonhaemorrhagic, 0.5% haemorrhagic and 1.3% uncertain. The following factors appeared as independent predictors for an increased risk of stroke: age, hazard ratio and 95% confidence interval (1.07; 1.05-1.08), a history of diabetes mellitus (2.4; 1.8-3.4), a history of stroke (2.3; 1.5-3.5), a history of hypertension (2.0; 1.5-2.7) and a history of smoking (1.5;1.1-2.0). Most of these factors were also predictors of a nonhaemorrhagic stroke whereas no predictor of haemorrhagic stroke was found. Conclusion. Risk indicators for stroke long-term after AMI were increasing age, a history of either diabetes mellitus, stroke, hypertension or smoking.

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Section: Discussionsupporting

confidence: 52%

Factors associated with development of stroke long‐term after myocardial infarction: experiences from the LoWASA trial

Herlitz¹,

Holm²,

Peterson³

et al. 2005

Journal of Internal Medicine

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“…Ayrıca; alkol alınmasıyla kalp atışları artar ve damarlarda kan akışı hızlanır, kalp krizi geçirme riski artar (6). Sağlıklı beslenme ile KAH'na yol açan risk faktör-lerinden obezite, diyabetes mellitus, metabolik sendrom, dislipidemi ve hipertansiyon gelişimi geciktirilebilir veya azaltılabilir.…”

Section: Introductionunclassified

Effects of patient education and counseling about life style on quality of life in patients with coronary artery disease

Kurçer¹,

Özbay²

2011

Anadolu Kardiyol Derg

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ÖZETAmaç: Bu çalışma; koroner arter hastalarına (KAH) yaşam tarzı değişikliği konusunda yapılacak olan eğitim ve danışmanlık müdahalesinin hastaların aldıkları medikal, invaziv veya cerrahi tedavi tiplerine göre yaşam kalitesine etkisini saptamak amacıyla yapıldı. Yöntemler: Araştırmanın örneklemini KAH tanısı konulan 102 hastadan 18 yaşın üzerinde, algılama bozukluğu, iletişim sorunu olmama kriterleri karşılayan ve çalışmaya katılmayı kabul eden 82 hasta (%80.3) oluşturmuştur. Araştırma dizaynı prospektif kohorttur. Hastalara 'Hasta Bilgi Formu', 'SF-36 Yaşam Kalitesi Ölçeği' uygulanmış ve sağlıklı beslenme, fiziksel aktivite, sağlıklı vücut ağırlığının korunması, sigara ve alkolün bırakılması konularında eğitim ve danışmanlık müdahalesi yapılmıştır. Üç ay sonra hastalara tekrar 'Hasta Bilgi Formu', 'SF-36 Yaşam Kalitesi Ölçeği' uygulanarak müdahalenin etkinliği değerlendirilmiştir. Elde edilen verileri tekrarlı ölçümler için varyans analizi (ANOVAR), Ki-kare önem-lilik testi ve nonparametrik testlerden Wilcoxon işaret ve Kruskal-Wallis varyans testleriyle analiz edilmiştir. Bulgular: Hastalara verilen eğitim ve danışmanlık sonrasında, diyete uyumları ve egzersiz süreleri artmış, diyastolik kan basınç ortalaması düşmüş ve SF-36 yaşam kalitesi alan puanları yükselmiştir (tümü için p<0.05). Ancak eğitim ve danışmanlıktan sonra sistolik kan basınç ortalaması, hastaların beden kitle indeks ortalamaları, lipit düzeyleri, günlük içilen sigara sayısı ve alınan alkol kadeh miktarı anlamlı düzeyde değişmemiştir. Sonuç: KAH hastalarına yapılan eğitim ve danışmanlık müdahalesiyle, fiziksel aktivite artışının sağlandığı, diyete uyum düzeyinin arttığı, diyastolik kan basıncında anlamlı düzeyde azalma olduğu, SF-36 yaşam kalitesi ölçeğinin 8 skalasında da, pozitif yönde artma olduğu görülmüştür. ABSTRACTObjective: The aim of this study is to investigate the effects of patient education and counseling intervention success on quality of life (QoL) in patients with coronary artery disease patients. Methods: Sample of this study included 82 (80.3%) of total 102 patients diagnosed with coronary artery disease. Patients were older than 18 age and they had no perception and communication problems. QoL was measured by means of the Short Form-36 (SF-36) and then subscale scores were calculated in before getting the education and counseling intervention. Subject of education and counseling intervention consists of healthy nutrition, physical activity, maintaining healthy body weight, smoking and alcohol quit issues. After educations and counseling intervention three months later, Short Form-36 was administered. One way analyses of variance for repeated measures (ANOVAR), Chi-square significance test, t-test and nonparametric tests (Wilcoxon sign and Kruskal Wallis Variance) were used to compare demographic and clinic characteristic values of the patient's groups. Results: After education and counseling intervention, SF 36 QoL points, mean exercise duration and number of patients with well -adjusted diet program increased, and diastol...

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“…Cavender et al (1) present an analysis by using time-dependent covariates. The data are from the Coronary Artery Surgery Study (CASS), in which individuals with mild angina (i.e.…”

Section: Selecting the Form Of A Time-dependent Covariatementioning

confidence: 99%

Time-Dependent Covariates in the Cox Proportional-Hazards Regression Model

Fisher

Lin

1999

Annu. Rev. Public Health

Self Cite

844

599

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The Cox proportional-hazards regression model has achieved widespread use in the analysis of time-to-event data with censoring and covariates. The covariates may change their values over time. This article discusses the use of such timedependent covariates, which offer additional opportunities but must be used with caution. The interrelationships between the outcome and variable over time can lead to bias unless the relationships are well understood. The form of a timedependent covariate is much more complex than in Cox models with fixed (nontime-dependent) covariates. It involves constructing a function of time. Further, the model does not have some of the properties of the fixed-covariate model; it cannot usually be used to predict the survival (time-to-event) curve over time. The estimated probability of an event over time is not related to the hazard function in the usual fashion. An appendix summarizes the mathematics of time-dependent covariates.

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Effect of smoking on survival and morbidity in patients randomized to medical or surgical therapy in the coronary artery surgery study (CASS): 10-Year follow-up

Cited by 171 publications

References 22 publications

Factors associated with development of stroke long‐term after myocardial infarction: experiences from the LoWASA trial

Factors associated with development of stroke long‐term after myocardial infarction: experiences from the LoWASA trial

Effects of patient education and counseling about life style on quality of life in patients with coronary artery disease

Time-Dependent Covariates in the Cox Proportional-Hazards Regression Model

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