Effect of sodium, amine and stannous fluoride at the same concentration and different pH on in vitro erosion

Abstract

Effect of sodium, amine and stannous fluoride at the same concentration and different pH on in vitro erosion Abstract OBJECTIVE: This study aimed to compare the effects 0.5% and 1% sodium, amine and stannous fluoride at different pH on enamel erosion in vitro. METHODS: Bovine enamel samples were submitted to a cyclic de-and remineralisation for 3 days. Each day, the samples were exposed for 120 min to pooled human saliva and subsequently treated with one of the fluoride solutions for 3 min: amine fluoride (AmF, 0.5% and 1% F(-)), sodium fluoride (NaF, 0.5% and 1% F(-)), each at pH 3.9 and 7.0, and stannous fluoride (SnF(2), 0.5% and 1% F(-)), at pH: 3.9. Additionally, two groups were treated with fluoride-free placebo solutions (pH: 3.9 and 7.0) and one group served as control (no fluoridation).Ten specimens each group were inserted in a so-called artificial mouth and eroded six times daily with hydrochloric acid (pH 2.6) for 90 s each intermitted by exposure to artificial saliva (1h). After 3 days, enamel loss was analyzed profilometrically and evaluated statistically by ANOVA. RESULTS: Only the acidic 0.5% and 1% SnF(2) and 1% AmF solutions were able to reduce erosive enamel loss significantly, while all other solutions and placebos did not differ significantly from the control. Between the acidic SnF(2) and the 1% AmF solutions no significant differences could be detected. CONCLUSION: At the same concentrations, acidic SnF(2) and AmF may be more effective than NaF to protect enamel against erosion. Objective: This study aimed to compare the effects 0.5% and 1% sodium, amine and stannous fluoride at different pH on enamel erosion in vitro.Methods: Bovine enamel samples were submitted to a cyclic de-and remineralisation for three days. Each day, the samples were exposed for 120 min to pooled human saliva and subsequently treated with one of the fluoride solutions for 3 min: amine fluoride (AmF, 0.5% and 1% F -), sodium fluoride (NaF, 0.5% and 1% F -), each at pH 3.9 and 7.0, and stannous fluoride (SnF 2 , 0.5% and 1% F-), at pH: 3.9. Additionally, two groups were treated with fluoride-free placebo solutions (pH: 3.9 and 7.0) and one group served as control (no fluoridation). Ten specimens each group were inserted in a so-called artificial mouth and eroded six times daily with hydrochloric acid (pH 2.6) for 90 s each intermitted by exposure to artificial saliva (1h). After three days, enamel loss was analysed profilometrically and evaluated statistically by ANOVA. Results:Only the acidic 0.5% and 1% SnF 2 and 1% AmF solutions were able to reduce erosive enamel loss significantly, while all other solutions and placebos did not differ significantly from the control. Between the acidic SnF 2 and the 1% AmF solutions no significant differences could be detected.

Topical fluoride application is able to reduce acid susceptibility of restorative materials

“…This is possibly because the precipitates formed by application of native AmF had less solubility in citric acid thus providing a protective barrier to conventional glassionomer cement and polyacid-modified resin composite surface against erosive attack 3) . Further, the surfactant properties of AmF might contribute to its superior erosion-prohibiting potential compared to other fluoride measures 33) .…”

“…Generally speaking, the strategy of the fluoride application is to render the tooth tissue more resistant against acid attacks 1) . In literature, a number of studies showed that fluoride application is able to reduce erosive substance loss, calcium release, and surface softening of enamel and dentine [2][3][4][5][6][7] . Overall, although clinical studies regarding the erosion-inhibiting potential of fluoridation are not yet available, the protective effect of fluoride application on erosion progression have been shown both in vitro and in situ.…”

The effect of saliva substitutes on enamel erosion in vitro

“…The de-/remineralization cycle was performed in a so-called artificial mouth 13 allowing alternating erosion and remineralization of the specimens under standardized conditions in chambers, which are connected to two multichannel pumps (acid solution and artificial saliva). The specimens were subjected to the artificial mouth for 3 days with six erosive attacks daily.…”

Influência da frequência de aplicação da solução de AmF/NaF/SnCl2 no seu potencial em inibir a progressão da lesão de erosão no esmalte dental humano

“…Dentre eles, preparações contendo estanho associado a fluoretos provaram ser muito eficazes na redução da desmineralização erosiva (Ganss et al 2004(Ganss et al , 2008(Ganss et al , 2010a(Ganss et al , 2010b(Ganss et al , 2012b(Ganss et al , 2014(Ganss et al , 2015Schlueter et al, 2009aSchlueter et al, , 2009bSchlueter et al, , 2009cSchlueter et al, , 2009dSchlueter et al, , 2009e, 2010Schlueter et al, , 2011aSchlueter et al, , 2013Schlueter et al, , 2014Hove et al, 2006Wiegand et al, 2009;Yu et al, 2010aYu et al, , 2010bComar et al, 2012;Huysmans et al, 2011;Stenhagen et al, 2013;Rakhmatullina et al, 2013;Lussi, 2014).…”

“…Estudos in vitro (Sorvari et al, 1994;Büyükyilmaz et al, 1997;Ganss et al, 2001;vanRijkom et al, 2003;Vieira et al, 2005;Hove et al, 2006;Lagerweij et al, 2006;Schlueter et al, 2007;Ganss et al, 2008;Wiegand et al, 2009;Yu et al, 2010a,b) e in situ (Ganss et al, 2004;Schlueter et al, 2009aSchlueter et al, , 2011aWiegand et al, 2010a;Mathews et al, 2012) mostraram a eficácia de diferentes produtos fluoretados na proteção e remineralização de lesões de erosão em esmalte dental. A maioria destes estudos avaliou compostos fluoretados utilizados que apresentam eficácia comprovada na prevenção e controle da cárie dental, como fluoreto de sódio (NaF), fluoreto de amina (AmF), fluoreto de estanho (SnF 2 ) e tetrafluoreto de titânio (TiF 4 ), os quais apresentam diferentes interações com o tecido mineralizado dental.…”