A field experiment was conducted at the Agronomy Field Laboratory, Bangladesh Agricultural University from November 2016 to March 2017 to find out the effect of irrigation regimes and nitrogen (N) fertilization on the yield performance of spring wheat. The experiment was comprised five levels of irrigation viz., no irrigation (I0); CRI (crown root initiation stage) (I1); CRI + maximum tillering stage (I2); CRI + maximum tillering stage + flowering Stage (I3); CRI + maximum tillering stage + flowering stage + grain formation stage (I4); and six levels of nitrogen viz., 0, 60, 80, 100, 120 and 140 kg ha -1 under Split Plot design with three replicates. Except few all the yield contributing characters and yield of wheat were significantly influence by the application of irrigation and nitrogen. The highest number of total tillers hill -1 (4.15), effective tillers hill -1 (3.63), number of spikelets spike -1 (14.67), grain yield (2.862 t ha -1 ), straw yield (3.45 t ha -1 ), biological yield (6.312 t ha -1 ) and harvest index (45.34%) were obtained from two irrigation at CRI+ Maximum tillering stage. In nitrogen management, the highest plant height (91.17 cm), number of spikelets spike -1 (15.24), number of grains spike -1 (44.46), spike length (10.89 cm), grain yield (2.93 t ha -1 ), straw yield (3.478 t ha -1 ) and biological yield (6.408) and harvest index (45.72%) were obtained from application of 120 kg N ha -1 . In interaction, the highest grain (3.897 t ha -1 ), straw (4.76 t ha -1 ) and biological yield (8.661 t ha -1 ) and harvest index (45.02%) were achieved from two irrigation at CRI + maximum tillering stage with application of 120 kg N ha -1 . The lowest grain yield (1.22 t ha -1 ) was achieved from one irrigation at CRI with no nitrogen application. Whereas, the lowest straw (2.13 t ha -1 ) and biological yield (3.78 t ha -1 ) were achieved from no irrigation with 60 kg N ha -1 . Based on these results it may conclude here that farmers may apply two irrigations (one at CRI and another at maximum tillering stage) with 120 kg N ha -1 to obtain the higher yield of wheat under Bangladesh context.