Effect of solvation on the synthesis of MOF-based microrobots and their targeted-therapy applications

Abstract

Magnetically-driven mobile micro/nanorobots have a significant influence on the application and development of intelligent targeted drug delivery. However, the potential risk of biological toxicity is one of the major main...

Development of 2D MOF-Based Microrobots under Annealing Treatment and Their Biomedical Application

“…Among them, magnetic field can provide the micro/nanorobots with real-time control signals over a long range and enable precise transportation of payload through remote control. Moreover, the magnetic field has minimal health risk; thus, wireless control through magnetic actuation is suitable for in vivo applications , such as cargo delivery and noninvasive surgery. Magnetic micro/nanorobots appear to be ideal for the next generation of targeted therapeutic technologies, but research to develop micro/nanorobots with favorable properties for drug delivery is still in the early stages.…”

Micro-/nanoscale robotics for chemical and biological sensing

“…56 A recent publication by Mu's team reported the preparation of MOF-based microrobots. 57 This method relies on the use of sacrificial photoresist platforms used to help release the robots from the substrate for further treatment after a series of metal film deposition using RF magnetron sputtering. Microrobots of different shapes could be created using photomasks having different designs.…”

Propulsion of Planar V‐Shaped Microswimmers in a Conically Rotating Magnetic Field

“…[31,32] Despite recent theoretical advances in comprehending the driven propulsion of planar magnetic microswimmers, there is no systematic experimental investigation testing the role of geometry, magnetization, or field frequency and configuration, other than the experiment with the upscaled (cm-sized) 3D-printed propellers by Sachs et al [30] The use of planar microswimmers, which can be mass-produced through standard photolithography, is an attractive option in the field of microrobotics due to its ease of fabrication and potential for scalability and biocompatibility. [33,34] Planar magnetic microswimmers are prone to magnetize in their plane, while in-plane magnetized microswimmers typically exhibit bidirectional propulsion (i.e., parallel and antiparallel to the fieldrotation axis) when driven by a standard in-plane rotating magnetic field. [29,30] Unidirectional propulsion requires an off-plane magnetization, which is a nontrivial undertaking.…”

“…[ 31,32 ] Despite recent theoretical advances in comprehending the driven propulsion of planar magnetic microswimmers, there is no systematic experimental investigation testing the role of geometry, magnetization, or field frequency and configuration, other than the experiment with the upscaled (cm‐sized) 3D‐printed propellers by Sachs et al [ 30 ] The use of planar microswimmers, which can be mass‐produced through standard photolithography, is an attractive option in the field of microrobotics due to its ease of fabrication and potential for scalability and biocompatibility. [ 33,34 ]…”