Effect of some Indian herbs on macrophage functions in ochratoxin A treated mice

Dhuley, Jayant N

doi:10.1016/s0378-8741(97)00072-x

Cited by 98 publications

(56 citation statements)

References 11 publications

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“…Most of the plants so far reported for immunomodulatory effects have major effects on non-specific immunity, i.e. macrophage functions (Atal et al 1986;Dhuley 1997). …”

Section: Discussionmentioning

confidence: 99%

Effect of Cinnamomum zeylanicum Essential Oil on Antioxidative Status in Broiler Chickens

et al. 2009

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The experiment was conducted to investigate the effects of Cinnamomum zeylanicum essential oil on antioxidant status of chickens. Thirty-two female Ross 308 hybrid broilers were fed one of four diets supplemented with 0%, 0.1%, 0.05% and 0.025% of essential oil for 38 days. Blood, liver, kidney and duodenal epithelium were collected for the subsequent evaluation of antioxidant status. Feeding of adiet supplemented with 0.1% of essential oil significantly decreased the concentration of malondialdehyde (MDA) in plasma and duodenal mucosa in comparison with the control group (0%). The activities of glutathione peroxidase (GPx) were significantly higher in blood of chicks fed the diet containing 0.1% of essential oil. Diets containing 0.05% and 0.025% of essential oil reduced alanine amino transferase (ALT) activity in plasma in comparison with the control group. Blood phagocytic activity significantly increased in chickens fed the diet supplemented with 0.1% and the index of phygocytic activity was affected by the diet containing 0.025% of essential oil in comparison with the control group. The present investigation shows that Cinnamomum zeylanicum essential oil exhibits a significant antioxidant activity in fattening chickens and can be used as a source of antioxidant in dietary supplement.

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“…Most of the plants so far reported for immunomodulatory effects have major effects on non-specific immunity, i.e. macrophage functions (Atal et al 1986;Dhuley 1997). …”

Section: Discussionmentioning

confidence: 99%

Effect of Cinnamomum zeylanicum Essential Oil on Antioxidative Status in Broiler Chickens

et al. 2009

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“…Root extract is cardioprotective (Khanna et al 1991). Plant extract is: antitumor (Kamat et al 2000), antifungal, anti-ulcer (Sairam et al 2003), immunostimulatory (Dhuley 1997), and diuretic (Balansand & Rayband 1987). The crude saponins from the shoots are useful in dyspepsia (CSIR 1992).…”

Section: Sweet Flag Sweet Sage (E)mentioning

confidence: 99%

Indigenous Use and Ethnopharmacology of Medicinal Plants in Far-West Nepal

Kunwar

Uprety

Burlakoti

et al. 2009

Ethnobot. Res. App.

346

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Ethnopharmacological knowledge is common and import among tribal populations but much of the information is empirical at best lacking scientific validation. Despite widespread use of plant resources in traditional medicines, bioassay analysis of very few plant species have been conducted to investigate their medicinal properties, and to ascertain safety and efficacy of traditional remedies. The present study analyses indigenous uses of medicinal plants of far-west Nepal and compares with earlier ayurveda studies, phytochemical assessments and pharmacological actions. A field study was carried out in Baitadi and Darchula districts of far-west Nepal. Group discussions, informal meetings, questionnaire surveys and field observations were employed for primary data collection. Voucher specimens were collected with field notes and codes and deposited at Tribhuvan University Central Herbarium (TUCH), Kathmandu. Only 50% of species surveyed shared common uses with ayurvedic medicine. This implies that these herbal remedies are part of an independent health care system in the Nepal Himalaya, which is indigenous and influenced by ayurveda. The folk uses of some of the species were contradicting to those of ayurveda and phytochemical bioassays. A detailed phytochemical study on those species would be an important line of research. IntroductionMedicinal plants help in alleviating human suffering and are widely used for subsistence, home remedies, and trade (Kunwar et al. 2006). It is estimated that 70-80% of people worldwide rely on traditional herbal medicine to meet their primary health care needs (Farnsworth & Soejarto 1991). The ayurveda is an ancient traditional system of medicine with remedies for health and alleviation of illness. The acceptance of the ayurveda is gearing up and use of indigenous drugs of natural/plant origin is a maPublished: January 16, 2009 Ethnobotany Research & Applications 6www.ethnobotanyjournal.org/vol7/i1547-3465-07-005.pdf cuna pruriens (L.) DC. for Parkinson's disease, Commiphora as a hypolipidemic, Asclepias as cardiotonic, psoralens for vitiligo, curcumines for inflammation, baccoside for mental retention, picrosides for hepatoprotective, diosgenin for the synthesis of steroidal hormones, guggulsterons as hypolipidemic, piperidine as bioavailability enhancers, asarone as hallucinogenic, phyllanthins as anti-virals, withanolides and many other steroidal lactones and their glycosides as immunomodulators (Jain 1994, Patwardhan 2000. As an example, the sale of drugs derived from the plant Taxus The increasing use of traditional therapies demands more scientifically sound evidence for the principles behind therapies and for effectiveness of medicines (Patwardhan et al. 2005). The therapies are often criticized due to dearth of research, critical evaluation, in vivo studies and validations (Fong 2002, Houghton 1995 to support the safety of uses. At the same time, ethnopharmacological knowledge is percolating down these days among the tribal population. The present study, therefore aim...

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“…These include antimutagenic, antitumor, antifungal (Edenharder 1990, Shimoyamada et al 1990, Shao et al 1996, diuretic (Balansard & Rayband 1987) and immunostimulatory effects (Thatte & Dahanukar 1988, Rege et al 1999, Dhuley 1997. A. racemosus has been considered to be a lactogogue in lactational inadequacy (Sharma et al 1996) and useful to decrease post-operative adhesions (scars; Rege et al 1999).…”

Section: Introductionmentioning

confidence: 99%

Insulin secretory actions of extracts of Asparagus racemosus root in perfused pancreas, isolated islets and clonal pancreatic β-cells

Hannan¹,

Marenah²,

Ali³

et al. 2007

Journal of Endocrinology

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Asparagus racemosus root has previously been reported to reduce blood glucose in rats and rabbits. In the present study, the effects of the ethanol extract and five partition fractions of the root of A. racemosus were evaluated on insulin secretion together with exploration of their mechanisms of action. The ethanol extract and each of the hexane, chloroform and ethyl acetate partition fractions concentration-dependently stimulated insulin secretion in isolated perfused rat pancreas, isolated rat islet cells and clonal b-cells. The stimulatory effects of the ethanol extract, hexane, chloroform and ethyl acetate partition fractions were potentiated by glucose, 3-isobutyl-1-methyl xanthine IBMX, tolbutamide and depolarizing concentration of KCl. Inhibition of A. racemosus-induced insulin release was observed with diazoxide and verapamil. Ethanol extract and five fractions increased intracellular Ca 2C , consistent with the observed abolition of insulin secretory effects under Ca 2C -free conditions. These findings reveal that constituents of A. racemosus root extracts have wide-ranging stimulatory effects on physiological insulinotropic pathways. Future work assessing the use of this plant as a source of active components may provide new opportunities for diabetes therapy.

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Effect of some Indian herbs on macrophage functions in ochratoxin A treated mice

Cited by 98 publications

References 11 publications

Effect of Cinnamomum zeylanicum Essential Oil on Antioxidative Status in Broiler Chickens

Effect of Cinnamomum zeylanicum Essential Oil on Antioxidative Status in Broiler Chickens

Indigenous Use and Ethnopharmacology of Medicinal Plants in Far-West Nepal

Insulin secretory actions of extracts of Asparagus racemosus root in perfused pancreas, isolated islets and clonal pancreatic β-cells

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