Effect of Sonographically Guided Cerebral Glioma Surgery on Survival Time

Abstract

Sonographically guided resection of cerebral gliomas helps the surgeon understand the relationship between the lesion and the surrounding structures. It is of value in improving the prevalence of total tumor resection and the patient's survival time.

Contrast-enhanced MR Imaging versus Contrast-enhanced US: A Comparison in Glioblastoma Surgery by Using Intraoperative Fusion Imaging

“…Another solution is the use of intraoperative MR imaging, CT, or US (10)(11)(12)(13)(14). The first two modalities take into TECHNICAL DEVELOPMENTS: Contrast-enhanced MR Imaging versus Contrast-enhanced US for Glioblastoma Prada et al started to study the contrast material kinetics in the lesion from the arrival in major vessels to the washout; usually the cine clip was registered for at least 100 seconds (range, 100-300 seconds), enabling study of the lesion on both the main axis and the entire volume, along with whole vascular phases.…”

The value of intraoperative sonography in low grade glioma surgery

“…On the other hand, neuronavigation allows an accurate localization of the tumor, but it cannot exclude intraoperative dynamic changes of brain shift, which can be initiated by the loss of cerebrospinal fluid, tumor debulking or even brain deformation caused by positioning of the head [3].…”

“…There is a number of studies which focus on distinguishing normal brain tissue from residual tumor ultrasonographically since intraoperative sonography is an easy to handle, inexpensive modality and most important, real-time, which is not affected by brain shift [3,15]. On the other hand, neuronavigation allows an accurate localization of the tumor, but it cannot exclude intraoperative dynamic changes of brain shift, which can be initiated by the loss of cerebrospinal fluid, tumor debulking or even brain deformation caused by positioning of the head [3].…”

“…It has been shown that surgical extension of a tumor, as well as the tumor grade is essential for the prolonged survival of glioma patients [1][2][3]. There are different methods, which are helpful to localize the glioma and allow extended tumor resection, such as 5-aminolevulinic acid, intraoperative MRI as well as intraoperative ultrasound [2,[4][5][6][7].…”

“…At the beginning of the use of ultrasound by Reid in 1978 [11] the image quality was low therefore the method was not used by neurosurgeons routinely. Today the technology of ultrasound has been improved significantly, providing the surgeon with a very valuable tool in identifying the tumor [12] and even make a preliminary diagnosis of the tumor as low or high grade glioma [3].…”