Effect of stannous fluoride mouthrinse on dental plaque formation

Tinanoff, Norman; Hock, Janet M.; Camosci, David; Helldén, Leif

doi:10.1111/j.1600-051x.1980.tb01966.x

Cited by 54 publications

(24 citation statements)

References 19 publications

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“…Since the introduction of chlorhexidine in the plaque control in the early 70s, several alternative plaque inhibitors with clear-eut effect as compared with placebo have been tested (5)(6)(7)(8). However, when compared with chlorhexidine none has shown equal or better activity without also giving unacceptable side effects (9)(10)(11)(12).…”

mentioning

confidence: 99%

Effectiveness of Veadent as a plaque‐inhibiting mouthwash

Abbas

Thrane

Othman

1985

European J Oral Sciences

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Abbas DK, Thrane P, Othman SJ: Effectiveness of Veadent as a plaque-inhibiting mouthwash. Scand J Dent Res 1985; 93: 494-7. Abstract ~ The aim of this study was to compare the effect of the commercially available Veadent mouthwash and chlorhexidine on plaque formation. Plaque accumulating during two 5-day periods was recorded in a group of 10 students. During the experimental periods, the test subjects abstained from mechanical cleaning of the teeth, and chewed sucrose-containing chewing gum every 4th h in order to enhance plaque formation. They also rinsed with cither chlorhexidine or Veadent twice a day according to the manufacturer's recommendations. Chlorhexidine mouthrinses resulted in significantly lower plaque scores than did Veadent in the present shortterm model study..: '..•

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mentioning

confidence: 99%

Effectiveness of Veadent as a plaque‐inhibiting mouthwash

Abbas

Thrane

Othman

1985

European J Oral Sciences

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“…Dentifrices with triclosan and copolymer or a zinc salt have demonstrated anticaries activity [154] even in long-term studies [155]. In high-risk patients, amine and stannous fluoride may also be recommended based on the proven remineralization and anticaries action [156,157]. • In the prevention of recurrent aphthous ulcers.…”

Section: Indications Of Toothpastes With Plaque Inhibitory And/or Antmentioning

confidence: 99%

Antiplaque and Antigingivitis Toothpastes

Sanz

Serrano

Iniesta

et al. 2013

Monographs in Oral Science

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Dentifrices are a general term used to describe preparations that are used together with a toothbrush with the purpose to clean and/or polish the teeth. Active toothpastes were first formulated in the 1950s and included ingredients such as urea, enzymes, ammonium phosphate, sodium lauryl sarcosinate and stannous fluoride. Later, therapeutic agents were included. Today's toothpastes have two objectives: to help the toothbrush in cleaning the tooth surface and to provide a therapeutic effect. The therapeutic effect may have an antiplaque or anti-inflammatory basis when the nature of the agents is antimicrobial. Plaque inhibitory and antiplaque activity of toothpastes used for chemical plaque control is evaluated in distinct consecutive stages, the last being home use randomized clinical trials of at least 6 months' duration. In this chapter, the scientific evidence supporting the use of the most common antiplaque agents, included in toothpaste formulations, is reviewed, with a special emphasis on 6-month clinical trials, and systematic reviews with meta-analyses of the mentioned studies. Among the active agents, the following have been included in toothpastes: enzymes, amine alcohols, herbal or natural products, triclosan, bisbiguanides (chlorhexidine), quaternary ammonium compounds (cetylpyridinium chloride) and different metal salts (zinc salts, stannous fluoride, stannous fluoride with amine fluoride). Dentifrices are the ideal vehicles for any active ingredient used as an oral health preventive measure since they are used in combination with toothbrushing, which is the most frequently employed oral hygiene method. The most important indications of dentifrices with active ingredients are associated with long-term use to prevent bacterial biofilm formation, mostly in gingivitis patients or in patients on supportive periodontal therapy.

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“…The local delivery of antimicrobial agents into the periodontal pocket is considered to have excellent potential as an adjunct to traditional periodontal therapy. The following local delivery systems have been tried for different agents: dentifrices ( 34), mouthrinses ( 35, 36), dental gels ( 37, 38), irrigation devices ( 39–41) and professional administration into the pocket by means of syringes.…”

Section: Conventional Antimicrobial Therapeuticsmentioning

confidence: 99%

Controlled and targeted drug delivery strategies towards intraperiodontal pocket diseases

2000

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Advances in the understanding of the aetiology, epidemiology, pathogenesis and microbiology of periodontal pocket flora have revolutionized the strategies for the management of intraperiodontal pocket diseases. Intra‐pocket, sustained release, drug delivery devices have been shown to be clinically effective in the treatment of periodontal infections. Several degradable and non‐degradable devices are under investigation for the delivery of antimicrobial agents into the periodontal pocket including non‐biodegradable fibres, films (biodegradable and non‐biodegradable), bio‐absorbable dental materials, biodegradable gels/ointments, injectables and microcapsules. With the realization that pocket bacteria accumulate as biofilms, studies are now being directed towards eliminating/killing biofilm concentrations rather than their planktonic (fluid phase) counterparts. Intraperiodontal pocket drug delivery has emerged as a novel paradigm for the future research. Similarly, bioadhesive delivery systems are explored that could significantly improve oral therapeutics for periodontal disease and mucosal lesions. A strategy is to target a wide range of molecular mediators of tissue destruction and hence arrest periodontal disease progression. Research into regenerating periodontal structures lost as a result of disease has also shown substantial progress in the last 25 years.

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Effect of stannous fluoride mouthrinse on dental plaque formation

Cited by 54 publications

References 19 publications

Effectiveness of Veadent as a plaque‐inhibiting mouthwash

Effectiveness of Veadent as a plaque‐inhibiting mouthwash

Antiplaque and Antigingivitis Toothpastes

Controlled and targeted drug delivery strategies towards intraperiodontal pocket diseases

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