2024
DOI: 10.1002/pds.5775
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Effect of statin treatment on the risk of cancer in patients with heart failure: A target trial emulation study

Chengsheng Ju,
Wallis C. Y. Lau,
Pinkie Chambers
et al.

Abstract: PurposeA recent observational study suggested statins could reduce cancer diagnosis in patients with heart failure (HF). The findings need to be validated using robust epidemiological methods. This study aimed to evaluate the effect of statin treatment on the risk of cancer in patients with HF.MethodsWe conducted two target trial emulations using primary care data from IQVIA Medical Research Database‐UK (2000 to 2019) with a clone‐censor‐weight design. The first emulated trial addressed the treatment initiatio… Show more

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