Effect of statins on atherosclerotic plaque

Risk of Stroke in Systemic Necrotizing Vasculitis: A Nationwide Study Using the National Claims Database

“…Several different effects of statins could be considered in attenuating the risk of stroke in SNV. First, statins are effective in preventing atherosclerosis by reducing circulating low-density lipoproteins, and the attenuation of atherosclerotic lesions by statins could lead to a decreased incidence of stroke ( 43 ). Second, statins are able to provide non-lipid dependent vascular protective effects.…”

Novel Phytoconstituents of an Aqueous Pod Extract of Prosopis Cineraria (L.) Druce Attenuate Atherosclerotic Plaque and Hypercholesterolemia in Rabbits

“…Administration of the pod extract also caused a regression in the amount of atherosclerotic plaque and in the thickness of the aortal wall in hypercholesterolemic rabbits. Increased lumen volume was also observed in diseased rabbits treated with the pod extract which may have been due to the depletion of deposited fatty substances and increased oxidation of deposited fats as reported in earlier studies [8,[57][58][59][60]. Oxidative stress results from the excessive generation of free radicals in cells and leads to a number of metabolic disorders that affect the quality of life.…”

Effect of 2 Different Dosages of Rosuvastatin on Prognosis of Acute Myocardial Infarction Patients with New-Onset Atrial Fibrillation in Jinan, China

“…Statins can not only reduce TC and LDL-C, but can also strengthen collagen formation, thereby increasing plaque stability. Statins contribute to plaque regression by reducing lipid levels [ 32 ]. Multivariate Cox analysis in the present study showed that age, smoking, and drinking are independent risk factors associated with the occurrence of AF after adjusting for other factors.…”