Effect of Stellate Ganglion Block on Postoperative Recovery of Gastrointestinal Function in Patients Undergoing Surgery with General Anaesthesia: A Meta-Analysis.

Abstract

Background: The return of normal gastrointestinal function is an important signal of postoperative recovery in patients undergoing surgery with general anaesthesia, especially for abdominal surgery. Current methods to resolve this problem are conservative, and the effects are sometimes limited. We aimed to summarize the effects of stellate ganglion block(SGB) on the recovery of gastrointestinal function to explore methods for anaesthesiologists to contribute to postoperative patient recovery. RuMethods: Selected databases were searched for relevant studies. Study quality was assessed according to the Cochrane Collaboration’s tool for assessing risk of bias. Data extraction was performed independently. The time to peristaltic sound resumption, flatus, postoperative eating and the incidence and degree of abdominal bloating were compared between stellate ganglion and control groups. Meta-analysis was performed using Review Manager software. Results: In total, 281 studies were identified after searching for relevant articles, and five articles with data for 274 patients were eligible for this analysis. Regarding postoperative flatus time, SGB caused a mean reduction of 15 hours for different surgeries; after excluding a study causing heterogeneity, the mean reduction was still more than 6 hours. For gastrointestinal surgery, the mean reduction was approximately an entire day. When evaluating the recovery of peristaltic sounds in different surgeries, SGB promoted the recovery of regular bowl sounds by an average of 14.67 hours earlier than the control. With regard to nutrients, SGB shortened the total parenteral nutrition time by more than 50 hours in gastrointestinal surgery. Finally, SGB prevented the occurrence of postoperative abdominal bloating without influencing its degree. No complications related to SGB were reported. Conclusion: SGB promotes postoperative gastrointestinal recovery in patients undergoing different surgeries with general anaesthesia.

Clinical Study of Stellate Ganglion Block Combined with General Anesthesia on Hemodynamics, Cognitive Function, and Gastrointestinal Function in Elderly Patients Undergoing Partial Hepatectomy

“…It was confirmed by pathological examination as primary hepatocellular carcinoma. (ii) All patients met the surgical indications [8] and had not undergone minimally invasive treatment or biological treatment for hepatocellular carcinoma before enrollment. (iii) All patients were first-time patients; all signed the informed consent form.…”

Effects of Ultrasound-Guided Stellate Ganglion Block on Postoperative Quality of Recovery in Patients Undergoing Breast Cancer Surgery: A Randomized Controlled Clinical Trial

“…Early return of gastrointestinal function facilitates postoperative recovery of patients under general anesthesia. SGB can inhibit the excitation of the sympathetic nervous system, thereby restoring the balance of the autonomic nervous system and rebuilding the homeostasis of the neuroendocrine-immune system [32]. Furthermore, Zhao et al reported that SGB relieved symptoms of chronic ulcerative colitis [33].…”

SGB Postconditioning Improves Intestinal Barrier Function by Inhibiting Autophagy in Conscious Rats Following Hemorrhagic Shock and Resuscitation

“…In the experiment, we observed the loop blood ow of rats after hemorrhagic shock and found that the intestinal perfusion in the Shock group was signi cantly reduced, but the intervention of SGB signi cantly increased the intestinal blood ow in the Shock group. A recent systematic review and meta-analysis of the effect of SGB on the recovery of gastrointestinal function in patients undergoing general anesthesia con rmed the effect of SGB in promoting gastrointestinal recovery after traumatic surgery, which was related to gastrointestinal blood vessels telangiectasis and gastrointestinal motility improvement through the blockage of sympathetic nerves that innervate the gastrointestinal system [23] . The present result suggests that SGB postprocessing improves the intestinal blood supply after hemorrhagic shock, which is bene cial for reducing intestinal damage.…”