In the present study, the relationship between heat treatment, grain size, and the creep rupture properties of Fe-33Ni-19Cr alloy was investigated. The microstructure analysis showed that Fe-33Ni-19Cr alloy consists of the austenite phase matrix and a small number of precipitates such as titanium nitride and titanium carbides. Fe-33Ni-19Cr alloy shows an increase in steady-state creep rate with increased grain size from 94 to 381 μm, due to the grain boundary sliding mechanism. The result also exhibited that the alloy that was subjected to creep test failed in ductile mode and cavitation at the grain boundaries. The fracture surface shows a transgranular fracture but an intergranular fracture at the recrystallized grains at the fracture area. Taken together, the result exhibited that the Fe-33Ni-19Cr alloy subjected lower heat treatment temperature possess a smaller grain size, which led to better creep property along with more excellent service life during operation.A superalloy is an alloy capable of withstanding high stresses and often highly oxidizing atmosphere and high temperatures, which often reach extreme temperatures surpassing 1200 C. 1 These harsh environments caused creep to be a serious issue when the alloys are used at high temperatures. Superalloys based on iron (Fe), nickel (Ni), and cobalt (Co) can be engineered to be highly resistant to creep. 2 Thus, superalloys have arisen as an ideal material to be used in high-temperature environments. Fe-Ni-Cr alloy is a solid solution strengthening ironnickel-based heat-resistant steel. 3 They are widely used in high-temperature environments, such as steam generator tubes, nuclear power reaction tubes, gas turbines, petrochemical and refinery industries, reformer tubes, furnace components, and pyrolysis tubes. 4 The operating temperature of the modern power plant is up to 760 C, and the steam pressures are more than 35 MPa. High-temperature failure mechanism includes creep,