Effect of substituents on reactivity and reaction mechanism observed in Sn reaction of some organophosphorus compounds: based on Physical organic methodologies

Abstract

The aminolyses of tetracoordinated organophosphorus compounds were investigated by varying substituents around phosphorus center or in nucleophile. The reactivity is expressed in terms of second-order rate constant, k 2 and measured conductometrically. 5.66 can be interpreted as S N 2 process, with greater extent of bond formation in TS than that of 1, 2.