Effect of Sucrose Acetate Isobutyrate (SAIB) Ingestion on the Hepatobiliary Function of Normal Human Male and Female Volunteers

Effect of Gum Arabic on Liver Function And Antioxidant Enzymes of Sprague-Dawley Rats

“…Another study on human subjects expressed the non effectiveness of 5g/ day gum Arabic dose on the total [3] study showed that gum Arabic dose reduced the total protein concentration in the liver tissue of mice. Upon searching the literature we did not find any study that registered increase in total proteins and albumin due to gum Arabic treatment in animals or humans; the results were ranging between either no effect or decreased the total proteins or albumin [3,12,16,17]. Regarding the Alanine transaminase (ALT) we have registered an insignificant increase in the blood level of ALT which reflect a cytotoxic effect of gum Arabic on liver cells.…”

“…However, Ghassan F. Alubaidy revealed that the daily 10g \ kg body weight decreased the total bilirubin. In another study using human subjects, Chiang M found that a mixture of sucrose acetate isobutyrate (SAIB), gum Arabic and orange juice did not affect the liver enzymes nor the direct bilirubin neither the total bilirubin [16].…”

“…One study found that the ALT was increased by gum Arabic dose [14] and some studies, registered reduced level of ALT [3,12,13]. A third research group concluded that the gum Arabic has no effect of ALT activity in humans or animals [16].…”