Effect of Supine Exercise on Left Ventricular Volume and Oxygen Consumption in Man

Gorlin, Richard; Cohen, Lawrence S.; Elliott, William C.; Klein, Michael D.; Lane, Francis J.

doi:10.1161/01.cir.32.3.361

Cited by 91 publications

(22 citation statements)

References 18 publications

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“…Gorlin et al (23) also noted only minimal changes in the left ventricular end-diastolic pressure during exercise in 20 patients without heart disease or with mild valvular lesions.…”

Section: Resultsmentioning

confidence: 95%

Cardiac hemodynamics in alcoholic patients with chronic liver disease and a presystolic gallop

Gould¹,

Shariff²,

Zahir³

et al. 1969

J. Clin. Invest.

121

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“…Gorlin et al (23) also noted only minimal changes in the left ventricular end-diastolic pressure during exercise in 20 patients without heart disease or with mild valvular lesions.…”

Section: Resultsmentioning

confidence: 95%

Cardiac hemodynamics in alcoholic patients with chronic liver disease and a presystolic gallop

Gould¹,

Shariff²,

Zahir³

et al. 1969

J. Clin. Invest.

121

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“…The increase in stroke volume that occurs between rest and exercise in the upright position is associated with an increase in totaJ heart size and left ventricular end-diastolic volume (69,152,285) . There is generaJ agreement that end-systolic volume decreases during exercise in both body positions (46, 69,117) . The role of the Starling mechanism during exercise in the supine position is controversiaJ (46, 69, 117, 296, 311, 348), however, perhaps because of methodologicaJ limitations.…”

Section: Postural Effects On Hemodynamic Responses To Exercisementioning

confidence: 92%

“…According to most (85 , 119, 120, 328) but not all (117,276) investigators, exercise in either position progressively increases left ventricular filling pressures, but pressures remain higher in the supine position (Fig. 6) .…”

Section: Postural Effects On Hemodynamic Responses To Exercisementioning

confidence: 96%

Cardiovascular Adjustments to Gravitational Stress

Blomqvist

Stone

1983

Comprehensive Physiology

198

163

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“…In addition, aortic cross-sectional area -a component of stroke volume determination by Doppler -was measured at different sites during exercise to assess its potential influence on the accuracy of the method. We sought to answer the following questions: (1) What is the technical feasibility of measuring cardiac output and stroke volume during exercise with Doppler and two-dimensional echocardiography? (2) What is the best method for measuring aortic diameter so that stroke volume can be calculated with Doppler?…”

mentioning

confidence: 99%

Determination of stroke volume and cardiac output during exercise: comparison of two-dimensional and Doppler echocardiography, Fick oximetry, and thermodilution.

Christie¹,

Sheldahl²,

Tristani³

et al. 1987

Circulation

181

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Simultaneous estimates of cardiac output were made during graded upright maximal exercise in 10 male subjects by means of Doppler velocity spectrum of ascending aortic flow, apical two-dimensional echocardiograms, thermodilution, and Fick oximetry. In 15 subjects, aortic annular and root diameters were measured during similar exercise from parasternal two-dimensional echocardiograms. The linear correlation between Doppler, two-dimensional echocardiography, and the invasive estimates ranged from r = .78 to r = .92. Both echocardiographic techniques were able to predict changes in invasive flow estimates with reasonable accuracy. Two-dimensional echocardiographic flow estimates underestimated invasive values by about 60%. The accuracy of Doppler flow estimates varied with the method of estimating aortic cross-sectional area. Greatest accuracy was obtained with areas calculated from diameters measured at the aortic value anulus with the leading edge-to-leading edge method of measurement. Correlation coefficients comparing Doppler and thermodilution flow estimates were generally higher (r = .75 to .96, mean .86) for individuals than for the group, but accuracy of the Doppler estimates in single subjects was quite variable. Aortic diameters did not increase from rest to moderate levels of upright exercise. A 3% to 5% increase in resting aortic diameter was noted in the upright posture as compared with the supine. Doppler flow estimates were obtained in all subjects to maximal exertion but in only a minority of subjects with two-dimensional echocardiography or thermodilution. Thus two-dimensional and Doppler echocardiography offer a noninvasive means of estimating cardiac output during vigorous exercise. The Doppler technique is technically more suitable to the study of exercise than two-dimensional echocardiography. Aortic area estimates for Doppler flow calculations are best made from resting two-dimensional echocardiograms of the aortic anulus by means of the leading edge-to-leading edge method of measurement. There does not appear to be a significant change in aortic diameter during upright exercise, but there may be a postural effect on aortic dimensions. Circulation 76, No. 3, 539-547, 1987. STROKE VOLUME and cardiac output are fundamental descriptors of cardiovascular function. Cardiac output is the primary indicator of the functional capacity of the circulation to meet the increased demands of physical exertion. The relative contributions of changes in stroke volume and heart rate to cardiac output and other factors influencing cardiac output 12 It was selected for this study because it allowed for rapid volume calculation from easily obtained and reproducible measurements. This formula has previously been validated in our laboratory by comparing it to left ventricular volume measured by left ventricular angiography in 20 patients with symmetric left ventricular wall motion. The correlation between echocardiographic and cineangiographic estimates of volume (range 42 to 232 ml) was .92 (echocardiog...

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Effect of Supine Exercise on Left Ventricular Volume and Oxygen Consumption in Man

Cited by 91 publications

References 18 publications

Cardiac hemodynamics in alcoholic patients with chronic liver disease and a presystolic gallop

Cardiac hemodynamics in alcoholic patients with chronic liver disease and a presystolic gallop

Cardiovascular Adjustments to Gravitational Stress

Determination of stroke volume and cardiac output during exercise: comparison of two-dimensional and Doppler echocardiography, Fick oximetry, and thermodilution.

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