Effect of supplementation of different boron and copper levels to layer diets on performance, egg yolk and plasma cholesterol

Olgun, Osman; Yazgan, Oktay; Çufadar, Yusuf

doi:10.1016/j.jtemb.2012.09.005

Cited by 21 publications

(6 citation statements)

References 17 publications

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“…[36][37][38][39] Animal studies have suggested that externally provided copper via diet could affect cholesterol levels. 37,40 When laying hens were fed a high copper diet (400 mg kg À1 ), the concentration of cholesterol in the liver was reduced by approximately 15%. 37 According to the studies by Wilmarth and coworkers, the levels of the transcription factors in the specific nuclear receptors (glucocorticoid receptor and farnesoid X receptor) involved in lipid metabolism and cholesterol/lipid biosynthesis were observed to be attenuated in the liver of an ATP7B knockout mouse model.…”

Section: Cholesterol Production Influenced By Metalsmentioning

confidence: 99%

Cholesterol and metal ions in Alzheimer's disease

et al. 2014

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Cholesterol and metal ions have been suggested to be associated with the onset and progression of Alzheimer's disease (AD). Moreover, recent findings have demonstrated a potential interconnection between these two factors. For example, (a) cholesterol has been shown to be misregulated in AD-afflicted brains, and the aberrant activity of proteins (particularly, apolipoprotein E (ApoE) and 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR)) has been linked to cholesterol-related AD exacerbation; (b) dyshomeostasis of metal ions associated with misfolded proteins (i.e., amyloid-β (Aβ) aggregates) found in the brains of AD patients is shown to promote oxidative stress leading to the malfunction of multiple proteins, including cytochrome c oxidase (CcO), and Cu/Zn superoxide dismutase (SOD1); (c) metal ion misregulation has also been observed to disrupt the activity of proteins (e.g., HMGR, low-density lipoproteins (LDL)), required for cholesterol production and regulation. Herein, we briefly discuss the potential involvement of cholesterol and metal ions in AD neuropathogenesis in both individual and interrelated manners.

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Section: Cholesterol Production Influenced By Metalsmentioning

confidence: 99%

Cholesterol and metal ions in Alzheimer's disease

et al. 2014

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“…Kurtoglu et al (2002) reported that B supplementation (50, 100, 150, 200 and 250 mg/kg) in laying hens increased serum levels of Ca and P. Similarly, Eren et al (2004) reported that the serum Ca, inorganic P and Mg levels were elevated in the laying hens fed on diets supplemented with boric acid for 8 weeks. Olgun et al (2012) observed that the addition of boron (60, 120 and 240 mg/kg) to layer ration significantly increased plasma B concentration. Amina et al (2017) reported that supplementing B at 100, 200 and 300 ppm significantly increased plasma Ca, P and B Boron Supplementation to Calcium Inadequate Diet Influences Mineral Content of Serum, Tissue and Antioxidant Status in... concentrations in laying hens.…”

Section: Mineral Content In Serum Bone Muscle and Livermentioning

confidence: 92%

Boron Supplementation to Calcium Inadequate Diet Influences Mineral Content of Serum, Tissue and Antioxidant Status in White Leghorn Layers

Vijay

Gowda

Pal

et al. 2021

IJAR

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Background: Boron (B), a novel micronutrient is known to influence utilization of macrominerals. Present study was conducted in layer birds to study the effect of B supplementation to inadequate calcium (Ca) diet on mineral content in serum, tissue and antioxidant status. Methods: A total of 80 commrcial White Leghorn layers, 25 weeks old with a uniform body weight were randomly assigned to one of the 4 groups of 20 hens in each dietary group viz., Normal calcium (NC), inadequate/low calcium (LC), Normal calcium with 40 ppm B (NCB) and inadequate/low calcium with 40 ppm B (LCB). Dietary level of calcium was maintained at 100 and 90% of the requirement and sodium borate was used as B source. At the end of feeding trial, blood and tissue samples were collected for estimating mineral and biochemical parameters. Result: Boron supplementation did not significantly alter the serum mineral content, serum alkaline phosphatase and total antioxidant activity but significantly (P less than 0.025) increased the superoxide dismutase activity in layers fed inadequate Ca diet. Boron supplementation to both diets significantly (P less than 0.03) increased phosphorus (P) content in bone and muscle, and magnesium (Mg) content in muscle (P less than 0.019). Boron supplementation to Ca inadequate diet significantly (P less than 0.006) enhanced the P and Mg content in liver. Content of B was significantly (P less than 0.01) higher in serum, bone and liver of hens supplemented 40 ppm of B. Implication of this study is amelioration of abiotic stress due to inadequate Ca intake with B supplementation. It is concluded that 40 ppm B supplementation positively influenced the Ca, P and Mg utilization and serum SOD activity.

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“…Jegede et al (2015) stated that adding 150 mg/kg Cu-proteinate to the laying hen diet reduced serum cholesterol concentration. Olgun et al (2013) reported that 75 and 300 mg/kg Cu levels in laying hens decreased serum HDL values compared to control and 150 mg/kg levels. El-Shafei et al ( 2012) reported that serum cholesterol values decreased with the addition of Cu to the diet.…”

Section: Serum Parametersmentioning

confidence: 95%

The Effect of Organic Copper Levels in Breeding Japanese Quail (Coturnix coturnix Japonica) Diets on Performance, Egg Quality, Incubation Parameters and Blood Parameters

Çufadar

Curabay

Gökmen

et al. 2022

J Hellenic Vet Med Soc

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This study was conducted to determine the effect of different levels of organic copper (organic Cu) supplementation on performance, egg quality, serum parameters and incubation characteristics in Japanese quail diets. 120 Japanese breeder quails of 7 weeks old were used in the study and lasted 84 days. Four diets containing different levels of organic copper (0, 75, 150 and 225 mg/kg) were used in the study. The study was a random design consisting of 20 subgroups with 5 replicates, and 4 females and 2 males were used in each subgroup. As a result of this study, final body weight and body weight gain in Japanese quails was significantly lower in the 75 and 150 mg/kg organic copper groups than in the groups containing 0 and 225 mg/kg copper (p<0.01; p<0.05). Egg production, egg weight, egg mass, feed intake and feed conversion ratio were not affected by dietary copper levels (p>0.05). Eggshell thickness and eggshell ratio were significantly higher in the groups containing 150 and 225 mg/kg organic copper than the control and 75 mg/kg organic copper groups (p<0.05). Serum cholesterol level was significantly lower in 75 and 150 mg/kg copper groups compared to other groups (p<0.05). Serum albumin, globulin and total protein levels were significantly lower in the 75 and 150 mg/kg copper groups compared to the control group (p<0.01). Serum albumin and total protein concentrations were significantly higher in the 75 and 150 mg/kg copper groups than the other groups (p<0.01). The highest serum calcium (Ca) level was in the group containing 225 mg/kg copper (p<0.01). In the study, incubation parameters were not significantly affected by different copper levels in the diet. The results of the study showed that adding 150 mg/kg of organic Cu to quail diets can be effective in improving eggshell quality.

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Effect of supplementation of different boron and copper levels to layer diets on performance, egg yolk and plasma cholesterol

Cited by 21 publications

References 17 publications

Cholesterol and metal ions in Alzheimer's disease

Cholesterol and metal ions in Alzheimer's disease

Boron Supplementation to Calcium Inadequate Diet Influences Mineral Content of Serum, Tissue and Antioxidant Status in White Leghorn Layers

The Effect of Organic Copper Levels in Breeding Japanese Quail (Coturnix coturnix Japonica) Diets on Performance, Egg Quality, Incubation Parameters and Blood Parameters

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Effect of supplementation of different boron and copper levels to layer diets on performance, egg yolk and plasma cholesterol

Cited by 21 publications

References 17 publications

Cholesterol and metal ions in Alzheimer's disease

Cholesterol and metal ions in Alzheimer's disease

​Boron Supplementation to Calcium Inadequate Diet Influences Mineral Content of Serum, Tissue and Antioxidant Status in White Leghorn Layers

The Effect of Organic Copper Levels in Breeding Japanese Quail (Coturnix coturnix Japonica) Diets on Performance, Egg Quality, Incubation Parameters and Blood Parameters

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Boron Supplementation to Calcium Inadequate Diet Influences Mineral Content of Serum, Tissue and Antioxidant Status in White Leghorn Layers