Effect of Synthesis Method of Bioactive Glasses on Acellular Bioactivity: Structural Analysis and Solid-State NMR Assessment

Baakili, Salwa El; Mabrouk, Khalil El; Bricha, Meriame

doi:10.2139/ssrn.4176056

Cited by 1 publication

(1 citation statement)

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“…BG coating accelerated the growth of new bone and made it easier for tissue to adhere strongly to implants [47] . Baekeli et al demonstrated that coating of 316 L stainless steel substrate with BG (15–7510 P/chitosan) resulted in rapid formation of thick and continuous HA layer on substrate and improved corrosion resistance [48] . Recently, homogenous, well adherent cohesive coating of 45S5 BG (Young's modulus 28±1.34 GPa and hardness 300±14.21 MPa) on Ti 6 Al 4 V implant enhanced corrosion resistance [49] .…”

Section: Bioactive Glasses (Bg) Their Types and Biomedical Applicationsmentioning

confidence: 99%

Bioactive Glass for Applications in Implants: A Review

Chand,

Malik,

Prasad

2024

ChemistrySelect

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Traditional metallic biomaterials including titanium and its alloys, stainless steel, cobalt‐chromium alloys, magnesium alloys are gold standards for load bearing hard tissue applications, because of adequate mechanical properties such as elastic modulus, ductility and strength for long term support and stability. However, metallic implants suffer from poor osteointegration and early degradation in host body, owing to an array of factors which include stress shieling effect, corrosion, metal toxicity, microbial contamination and low bioactivity. Therefore, to improve integration of implants with host tissue and overall mechanical and biological functions, metallic implants are coated with bioactive glasses (BG). BG are one of the most promising implant coating materials used for bone repair and reconstruction, mainly because of excellent angiogenic, osteoconductive, osteoinductive, corrosion resistance, resorbability, biocompatibility, bioactivity and anti‐microbial properties. Various BG compositions are employed for diverse biomedical applications ranging from wound healing, bone formation, corrosion resistance, drug delivery to scaffolds in tissue engineering and different methods are used for coating BG on implants to enhance stability and bond strength between implant and coating. This narrative review gives a detailed overview on metallic implants, issues of metal alloys when used in implants and how metallic implants are improved by various BG compositions and coating methods. This review provides an updated information on advantages of different BG compositions in implants fabrication in order to address challenges and tailor mechanical and biological properties of implants for future applications.

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Section: Bioactive Glasses (Bg) Their Types and Biomedical Applicationsmentioning

confidence: 99%