Effect of TAVR Approach and Other Baseline Factors on the Incidence of Acute Kidney Injury: A Systematic Review and Meta-Analysis

Alzu’bi, Hossam; Rmilah, Anan Abu; Haq, Ikram-UI; Kheiri, Babikir; Al‐Abdouh, Ahmad; Hasan, Bashar; Elsekaily, Omar; Jaber, Suhaib A.; Qaisi, Ibraheem; Yagmour, Asil; Dajani, Hamada; Ahmed, Azza M.; elhag, Ahmed; Kashani, Kianoush; Deshmukh, Abhishek

doi:10.1155/2022/3380605

Cited by 4 publications

(1 citation statement)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…From the baseline of this study, we observed that the via transfemoral pathway is more used, which inherently mitigated the risk of AKI development. Alzu'bi et al [25] investigated the risk of AKI following TAVR procedures conducted via transfemoral, transapical, and transaortic approaches. Their analysis revealed that patients undergoing the transfemoral approach exhibited a significantly lower risk of AKI compared to those undergoing transapical and transaortic approaches.…”

Section: Continuedmentioning

confidence: 99%

Comparison of the outcomes of concurrent versus staged TAVR combined with PCI in patients with severe aortic stenosis and coronary artery disease: a systematic review and meta-analysis

Zhang,

Geng,

Yan

et al. 2024

Coronary Artery Disease

View full text Add to dashboard Cite

Background The optimal timing for percutaneous coronary intervention (PCI) in patients undergoing transcatheter aortic valve replacement (TAVR) remains uncertain. This research aims to evaluate the results of patients diagnosed with severe aortic valve stenosis and coronary artery disease who undergo either simultaneous or staged PCI therapy during TAVR procedures. Methods We retrieved all relevant studies from our self-constructed databases up to January 2, 2024, encompassing databases such as Embase, Medline, Cochrane Library, and PubMed. Results A total of nine studies were included, and the results showed that both surgical modalities had good safety profiles in the early and long-term stages. For early endpoint events, the risk of all-cause mortality and major bleeding within 30 years was similar in the staged TAVR + PCI and the contemporaneous TAVR + PCI (P > 0.05). Additionally, the risk of myocardial infarction, stroke, acute kidney injury and pacemaker implantation within 30 days or perioperatively is similar (P > 0.05). For long-term endpoint events, the risk of all-cause mortality, myocardial infarction and stroke was similar in the two groups at ≥2 years (P > 0.05). Conclusion In patients undergoing TAVR who required coronary revascularization, no significant differences were observed in the early and long-term outcomes between those receiving concurrent TAVR and PCI versus staged surgery.

show abstract

Section: Continuedmentioning

confidence: 99%

Comparison of the outcomes of concurrent versus staged TAVR combined with PCI in patients with severe aortic stenosis and coronary artery disease: a systematic review and meta-analysis

Zhang,

Geng,

Yan

et al. 2024

Coronary Artery Disease

View full text Add to dashboard Cite

show abstract

Postoperative Acute Kidney Injury After Transcatheter Aortic Valve Replacement

Ayala,

Ma,

Peng

et al. 2024

Curr Anesthesiol Rep

View full text Add to dashboard Cite

Purpose of Review The purpose of this review serves to briefly summarize the current literature surveying the incidence of posttranscatheter aortic valve replacement acute kidney injury (TAVR AKI). Furthermore, this review extends itself to evaluate and potentially address modifiable risk factors, while acknowledging non-modifiable risk factors in the perioperative setting. These modifiable risk factors include but are not limited to access method, perioperative hypotension events, and need for blood transfusion in the setting of preoperative anemia. Recent Findings Recent retrospective studies have highlighted the incidence of post-TAVR AKI, citing as high as 1 in 6 patients. Despite exclusion of patients with end-stage renal disease (ESRD) from pivotal TAVR trials, data shows that over 50% of high-risk patients suffer > 3a chronic kidney disease (CKD) and about 10% of them suffer > 4 CKD, with the risk of AKI increasing significantly at each stage of CKD advancement. Meta-analyses have shown that patients who underwent TAVR via transfemoral (TF) approach compared to those who had transapical (TA) or transaortic (TaO) approach had significantly less AKI post-TAVR. Furthermore, in patients who developed post-TAVR AKI, 55% of them had received packed red blood cell (pRBC) transfusion, while only 21% of the patients who did not receive pRBCs develop post-TAVR AKI (p = .002). Post-TAVR AKI has been shown in multiple studies that it is an independent risk factor for increased short term and long-term mortality. These findings together highlight both the clinical significance and continued perioperative vigilance to further improve clinical outcomes. Summary This review aims to summarize recent literature regarding the association of AKI in the perioperative setting of TAVR. In addition, it parses the risk factors into both modifiable and non-modifiable risk factors. Furthermore, it provides some recommendations including procedure approach, appreciating transfusion implication, and most importantly, preventing hypotension events in the perioperative period.

show abstract

Acute Kidney Injury Following Transcatheter Aortic Valve Implantation—A Contemporary Perspective of Incidence, Predictors, and Outcomes

Butala,

Nanayakkara,

Navani

et al. 2024

Heart, Lung and Circulation

View full text Add to dashboard Cite

Effect of TAVR Approach and Other Baseline Factors on the Incidence of Acute Kidney Injury: A Systematic Review and Meta-Analysis

Cited by 4 publications

References 27 publications

Comparison of the outcomes of concurrent versus staged TAVR combined with PCI in patients with severe aortic stenosis and coronary artery disease: a systematic review and meta-analysis

Comparison of the outcomes of concurrent versus staged TAVR combined with PCI in patients with severe aortic stenosis and coronary artery disease: a systematic review and meta-analysis

Postoperative Acute Kidney Injury After Transcatheter Aortic Valve Replacement

Acute Kidney Injury Following Transcatheter Aortic Valve Implantation—A Contemporary Perspective of Incidence, Predictors, and Outcomes

Contact Info

Product

Resources

About