1995
DOI: 10.1093/bja/75.3.293
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Effect of temperature and cardiopulmonary bypass on the auditory evoked response

Abstract: We have recorded auditory evoked potentials before and during cardiopulmonary bypass in 10 adult patients undergoing cardiac surgery under moderate hypothermia to 27-28 degrees C. The immediate effect of bypass was a small decrease in latency and increase in amplitude of the early cortical response. We also studied two adults and two children during profound hypothermia with circulatory arrest during cardiopulmonary bypass. Reduction in core temperature to 25 degrees C resulted in an increase in latency and am… Show more

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Cited by 29 publications
(18 citation statements)
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“…In 1985, Doyle and Fria 39 reported altered brainstem audiometry results in monkeys under hypothermia, a finding also confirmed in humans by other authors 40,41 . Other indicators of neurologic and cochlear activity such as EEG and P300 tests are also impacted by hypothermia, as CNS metabolism decreases along with axonal conduction velocity and changes to the synaptic cleft are observed [39][40][41][42] . However, the effect of hypothermia on cochlear function can be better assessed by looking at OAEs.…”
Section: Discussionmentioning
confidence: 63%
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“…In 1985, Doyle and Fria 39 reported altered brainstem audiometry results in monkeys under hypothermia, a finding also confirmed in humans by other authors 40,41 . Other indicators of neurologic and cochlear activity such as EEG and P300 tests are also impacted by hypothermia, as CNS metabolism decreases along with axonal conduction velocity and changes to the synaptic cleft are observed [39][40][41][42] . However, the effect of hypothermia on cochlear function can be better assessed by looking at OAEs.…”
Section: Discussionmentioning
confidence: 63%
“…When analyzing the second possible mechanism for reduced DPOAE during hypothermia, one must bear in mind that the olivocochlear system has marked impact upon OHC function 40,41 . Such impact, however, inhibits OHC contraction as activity in the olivocochlear pathway is increased in the CNS 12,16 .…”
Section: Discussionmentioning
confidence: 99%
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“…Hett and colleagues [21] reported that the MLAEP was suppressed at 28 ЊC during CPB with decreased amplitude Anaesthesia, 1997, 52, pages 1048-1055 M. Doi et al…”
Section: Discussionmentioning
confidence: 99%
“…The AEPIndex reflects the morphology of AEP waveforms and is calculated from the amplitude difference between successive segments of the curve [19,20]. Although Hett and colleagues [21] reported the effect of hypothermia and CPB on AEP, changes of AEPIndex during cardiac anaesthesia have not been reported.…”
mentioning
confidence: 99%