The effect of the composition and temperature of the subphase on the effective dipole moment of the Langmuir monolayers of a liquid crystal 4-n-octyl-4’-cyanobiphenyl on the surface of pure water and an aqueous solution containing copper nanoparticles was studied. It is shown that the presence of nanoparticles in the subphase leads to increase of the area occupied by the monolayer in the condensed state, increase of the collapse pressure, and reduce of the surface potential at the end of monolayer compression. The effective dipole moments of liquid crystal molecules were calculated for monolayers formed under various conditions.