Effect of temperature, viscosity and surface tension on gelatine structures produced by modified 3D printer

Kalkandelen, Cevriye; Ozbek, Burak; Ergul, Necdet Mekki; Akyol, Sibel; Moukbil, Yunis; Oktar, FN; Ekren, Nazmi; Kılıç, Osman; Kılıç, Beyhan; Gündüz, Oğuzhan

doi:10.1088/1757-899x/293/1/012001

Cited by 5 publications

(2 citation statements)

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“…C−O and C−N bonds in 1525 cm −1 of pure gelatine in 1627 cm −1 were seen getting weakened after cross‐linking of composites. All of these changes showed strong evidence of the intermolecular interactions and good molecular compatibility between alginate and gelatine …”

Section: Resultsmentioning

confidence: 89%

“…FTIR analysis was used before and after crosslinking application. The spectrum demonstrates the characteristic absorption bands of the Gelatine including 1627 cm −1 , 1525 cm −1 , and 1234 cm −1 were attributed to Amide I, Amide II and Amide III, respectively and wide absorption band at around 3277 cm −1 was due to the stretching vibration of O−H bond of gelatine (Figure A(a)) . In Figure B(b), two characteristic absorption bands at 1594 cm −1 and 1405 cm −1 were detected and attributed to the asymmetric COO − group, 1023 cm –1 (C−O‐C stretching), respectively, and the characteristic peak of the free hydroxyl group was observed in the range of 3000 cm –1 to 3600 cm –1 were shown for Alg.…”

Section: Resultsmentioning

confidence: 92%

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3D Printing of Gelatine/Alginate/β‐Tricalcium Phosphate Composite Constructs for Bone Tissue Engineering

et al. 2019

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Bone tissue engineering studies have brought three‐dimensional scaffolds into focus that can provide tissue regeneration with designed porosity and strengthened structure. Current research has concentrated on the fabrication of natural and synthetic polymer‐based complex structures that closely mimic biological tissues due to their superior biocompatibility and biodegradabilities. Gelatine/Sodium Alginate hydrogels reinforced with different concentrations of β‐Tricalcium Phosphate (TCP) (10, 13, and 15 wt.%) were studied to form 3D bone tissue. Physical, mechanical, chemical, morphological properties and biodegradability of the constructs were investigated. Furthermore, in vitro biological assay with human osteosarcoma cell line (SAOS‐2) was performed to determine the biocompatibility of the constructs. It is found that cell viability rates for all constructs were increased and maximum cell viability rate was attained for 20%Gelatine/2%Alginate/10%TCP (wt.). The present work demonstrates that 3D printed Gelatine/Alginate/TCP constructs with porous structures are potential candidates for bone tissue engineering applications.

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Section: Resultsmentioning

confidence: 89%

Section: Resultsmentioning

confidence: 92%