Effect of the concentration and duration of methyltestosterone treatment on masculinization rate in the brown trout<i>(Salmo trutta)</i>

Chevassus, B.; Krieg, Francine

doi:10.1051/alr:1992031

Cited by 13 publications

(8 citation statements)

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“…In teleosts, the left gonad of the Argentine silverside, Odontesthes bonariensis [Strüssmann and Ito, 2005], was found to be the first to differentiate, and the size of the right ovary was often smaller than the left one in adult brown trout, Salmo trutta [Ashby, 1957], and rainbow trout [Mrsic, 1923]. Moreover, methyltestosterone treatment in trout can induce both a morphological and a molecular asymmetry of masculinization [Chevassus and Krieg, 1992;Guillevic and Guiguen, 2008]. These observations suggested that trout gonads may have an underlying asymmetrical differentiation program that is normally obscure but could be revealed under imbalanced physiological conditions.…”

Section: Discussionmentioning

confidence: 99%

Sex Differentiation in an All-Female (XX) Rainbow Trout Population with a Genetically Governed Masculinization Phenotype

Valdivia

Mourot

Jouanno

et al. 2013

Sex Dev

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Sex determination is known to be male heterogametic in the rainbow trout, Oncorhynchus mykiss; however, scattered observations that deviate from this rather strict genetic control have been reported. Here, we provide a detailed morphological and histological characterization of the gonadal differentiation and development (from 43 days postfertilization to 11 months of age) in an all-female (XX) population with a genetically governed masculinization phenotype. In comparison with control males and females, the gonadal differentiation in these animals was characterized by many perturbations, including significantly fewer germ cells. This decrease in germ cells was confirmed by the significantly decreased expression of 2 germ cell maker genes (vasa and sycp3) in the masculinized XX populations as compared with the control females and control males. Although only a proportion of the total adult population was partially or fully masculinized, this early differentiating phenotype affected nearly all the sampled animals. This suggests that the adult masculinization phenotype is the consequence of an early functional imbalance in ovarian differentiation in the entire population. We hypothesize that the lower number of germ cells that we observed in this population could be one cause of their masculinization.

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Section: Discussionmentioning

confidence: 99%

Sex Differentiation in an All-Female (XX) Rainbow Trout Population with a Genetically Governed Masculinization Phenotype

Valdivia

Mourot

Jouanno

et al. 2013

Sex Dev

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“…All these observations support the hypothesis of a ‘stronger femaleness’ of the left gonad, and are consistent with the observations that the right gonad is more sensitive to the mutation‐induced masculization. In contrast, however, following artificial masculinization with methyltestosterone in brown trout, Chevassus & Krieg (1992) observed the opposite, i.e . the right ovary was the most refractory to masculinization.…”

Section: Distribution Of Intersex Juvenile Rainbow Trout According Tomentioning

confidence: 99%

Asymmetry in sexual development of gonads in intersex rainbow trout

Quillet

Labbé

Queau

2004

Journal of Fish Biology

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“…Alternatively, the observed differences between the present study and that of Johnstone and Maclachlan (1994) may reflect the differences in treatment duration (800 degree-days compared with 500) between the studies. The duration of steroid exposure has been previously shown to affect the degree of sex inversion in salmonids (Chevassus and Kreig 1992;Piferrer and Donaldson 1992). Increased duration of both dietary (Chevassus and Kreig 1992) and immersion (Piferrer and Donaldson 1992) steroid treatments resulted in increased levels of sex inversion.…”

Section: Discussionmentioning

confidence: 98%

“…The duration of steroid exposure has been previously shown to affect the degree of sex inversion in salmonids (Chevassus and Kreig 1992;Piferrer and Donaldson 1992). Increased duration of both dietary (Chevassus and Kreig 1992) and immersion (Piferrer and Donaldson 1992) steroid treatments resulted in increased levels of sex inversion.…”

Section: Discussionmentioning

confidence: 98%

Preliminary Assessment of Sex Inversion of Farmed Atlantic Salmon by Dietary and Immersion Androgen Treatments

2004

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Dietary and immersion treatments with the androgens 17α‐methyltestosterone (MT) and 17α‐methyldihydrotestosterone (MDHT) were assessed for their efficacy in the masculinization of Atlantic salmon Salmo salar. Dietary treatments with MT at 1 or 3 mg/kg food or MDHT at 1 mg/kg food for 800 degree‐days resulted in 100% masculinization of all female stocks. Single or double immersion treatments of alevins in MDHT at 400 μg/L for 120 min during the period 0–28 d after median hatch resulted in significant masculinization. Immersion treatments were most effective when conducted more than 14 d after median hatch. Two immersion treatments 7 or 14 d apart resulted in masculinization levels of up to 100%, whereas single immersions yielded levels up to 77%. Immersion treatment resulted in the production of significantly more sex‐inverted males with patent sperm ducts than did dietary treatment. The study shows that immersion treatments are simple and effective for androgen‐induced masculinization of Atlantic salmon, that they are suitable for commercial‐scale use in hatcheries, and that they offer advantages in production efficiency over dietary treatments.

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Effect of the concentration and duration of methyltestosterone treatment on masculinization rate in the brown trout(Salmo trutta)

Cited by 13 publications

References 1 publication

Sex Differentiation in an All-Female (XX) Rainbow Trout Population with a Genetically Governed Masculinization Phenotype

Sex Differentiation in an All-Female (XX) Rainbow Trout Population with a Genetically Governed Masculinization Phenotype

Asymmetry in sexual development of gonads in intersex rainbow trout

Preliminary Assessment of Sex Inversion of Farmed Atlantic Salmon by Dietary and Immersion Androgen Treatments

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