usage of feed additive with 35 mg/head per day folic acid and trace elements complex in a dose of 10-50 mg/100 kg of live weight, Hexavit multivitamin 196 mg/head per day and similar trace elements, as well as all studied supplements in the diets of three groups of enceinte sows showed that dietary supplements activate anabolic processes in the body aimed at fetuses development and the deposition of reserve nutrients in the mother’s body. As a result, sows receiving the studied supplements gave more piglets by 18.6%, more good piglets to weaning - by 4.3%, in the cost structure the total costs decreased by 9.7 -18.5%. The complex use of all biologically active additives was not effective during the entire physiological period of pregnancy. With this, the following application scheme proved to be the most acceptable for metabolic processes’ stimulation in body: joint in the first 84 days of pregnancy and in the last 30 days - only folic acid with trace elements.